Abstract
A group of N-substituted 2-aminoacylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carbonitriles (1) was prepared from 2-amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-carbonitrile (A 1).
Cyclisation reactions usingA 1 and N-heterocyclic analogues thereof (A 2 andB 3) as starting materials gave derivatives of the following two new heterocyclic ring systems: [1]benzo-thieno[3,2-e][1,2,4]-triazolo[2,3-c]pyrimidine (B) and pyrido-[4′,3′∶4,5]thieno[3,2-e][1,2,4-triazolo][2,3-c]pyrimidine (C).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literatur
F. Sauter, Mh. Chem.99, 2100 (1968).
K. Gewald, Chem. Ber.97, 3571 (1965);K. Gewald, E. Schinke undH. Böttcher, l. c.99, 94 (1966).
M. Nakanishi, T. Tetsuji, H. Imamura undH. Maruyama, Jap. Pat. 72 13.676 (24. 4. 1972);A. Rosowsky, M. Chaykovsky, K. K. N. Chen, M. Lin undE. J. Modest, J. Med. Chem.16, 185 (1973).
M. Nakanishi, T. Tahara, O. Nakatsu, H. Imamura undY. Maruyama, Deutsche Offenlegungsschrift 1 812 404 (14. 8. 1969).
K. Eichenberger, P. Schmidt undE. Schweizer, Deutsche Offenlegungsschrift 1 937 459 (5. 2. 1970).
H. J. Kabbe, Deutsche Offenlegungsschrift 1 935 295 (14. 1. 1971).
R. A. Crochet, jr., undC. De Witt Blanton, jr., Synthesis1974, 55.
Author information
Authors and Affiliations
Additional information
Unserem verehrten Lehrer, Herrn o. Prof. Dr.O. Hromatka, in Dankbarkeit zum 70. Geburtstag gewidmet.
Rights and permissions
About this article
Cite this article
Sauter, F., Stanetty, P. Synthese neuer Derivate des 2-Amino-4,5,6,7-tetrahydro-benzo[b]thiophen-3-carbonitrils: basische Substitutions-produkte und anellierte Thieno-[1,2,4]-triazolo-pyrimidine. Monatshefte für Chemie 106, 1111–1116 (1975). https://doi.org/10.1007/BF00906224
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF00906224