Abstract
To test for cross-protective capacity of two different P-fimbriae vaccines we vaccinated baboons with fimbriae purified from eitherEscherichia coli strain ER2 or strain JR1. The vaccinated animals showed elevated antibody titers to P-fimbriae from each of theE. coli strains used, suggesting cross-reactivity as was expected from the results of immunoprecipitation of the fimbriae. Enzyme-linked immunosorbent assay inhibition by heterologous P-fimbriae proved this to be true immunologic cross-reactivity.
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Kaack, M.B., Pere, A., Korhonen, T.K. et al. P-fimbriae vaccines. Pediatr Nephrol 3, 386–390 (1989). https://doi.org/10.1007/BF00850212
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DOI: https://doi.org/10.1007/BF00850212