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Diversity of collagen expression in the pleomorphic adenoma of the parotid gland

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Summary

The high diversity of collagen expression and its qualitative and quantitative aspects are demonstrated in pleomorphic adenoma using electron microscopy and specific histochemical methods. Great variability was observed in the amount, distribution and characteristics of the collagen found in the various types of tissue normally present in this tumour. Both deficient polymerization and hyperpolymerization of collagen and the occurence of desmoplasia were observed. Evidence is presented to suggest a role for localized collagenolysis in the invasiveness of this neoplasia.

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Authors and Affiliations

  1. Department of Oral Pathology. Piracicaba Dentistry Shool, University of Campinas, Piracicaba, Brazil

    Sergio R. P. Line

  2. Ludwig Insitute for Cancer Research, São Paulo Branch, R. Prof. Antonio Prudente, 109-4, 01509, São Paulo-SP, Brazil

    Humberto Torloni

  3. Department of Histology and Embryology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

    Luiz C. U. Junqueira

Authors
  1. Sergio R. P. Line
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  2. Humberto Torloni
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  3. Luiz C. U. Junqueira
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Line, S.R.P., Torloni, H. & Junqueira, L.C.U. Diversity of collagen expression in the pleomorphic adenoma of the parotid gland. Vichows Archiv A Pathol Anat 414, 477–483 (1989). https://doi.org/10.1007/BF00781704

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  • DOI: https://doi.org/10.1007/BF00781704

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