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Enzymes of the jejunal enterochromaffine cells in man

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Zeitschrift für Zellforschung und mikroskopische Anatomie Abt. Histochemie Aims and scope Submit manuscript

Summary

A study of enzymatic equipment of enterochromaffine cells (e.c.) in jenual biopsies obtained with a Crosby capsule in normal humans and patients with nontropical sprue was undertaken. The following enzymes were demonstrated: alkaline phosphatase and adenosine triphosphatase (cell membrane), acid phosphatase (corpuscular), non-specific esterase (diffuse and corpuscular, predominantly eserine resistant, in corpuscular localization E 600 resistant), DPN- and TPN-diaphorases and dehydrogenases of lactic acid, malic acid, isocitric acid, glucoso-6-phosphoric acid, succinic acid, β-hydroxybutyric acid and α-glycerophosphoric acid. Enzyme activities were not equal in all cells suggesting some type of secretory cycle. In most patients with untreated nontropical sprue or with the disease in relapse e.c. were more numerous and hypertrophic with elevated activities of non-specific esterase and acid phosphatase. Implications of these results are briefly discussed.

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Authors and Affiliations

  1. Laboratory of Angiology, 1st Institute of Pathology and 2nd Research Unit of Gastroenterology, Medical Faculty of Charles University, Prague, Czechoslovakia

    Zdeněk Lojda & Přemysl Frič

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  1. Zdeněk Lojda
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  2. Přemysl Frič
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With 8 Figures in the Text, of which 2 in Colour

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Lojda, Z., Frič, P. Enzymes of the jejunal enterochromaffine cells in man. Histochemie 3, 455–461 (1964). https://doi.org/10.1007/BF00736422

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  • DOI: https://doi.org/10.1007/BF00736422

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