Skip to main content
Log in

Mesotheliomas of the tunica vaginalis testis and hernial sacs

  • Case Report
  • Published:
Virchows Archiv A Aims and scope Submit manuscript

Summary

Three histologically and immunohistochemically well-documented cases of mesothelioma of the tunica vaginalis testis and hernial sac are presented. Analysis and follow-up data on our three patients and a review of 30 previously reported cases have revealed a varied and often unpredictable clinical course. A classification into high- and lowgrade malignant tumours is suggested, based on clinical and pathological findings.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Abell MR, Holtz F (1968) Testicular and paratesticular neoplasms in patients 60 years of age and older. Cancer 21:852–870

    Google Scholar 

  • Amthor M, Falk S, Tuma F, Koch PM, Stutte HJ (1988) Das maligne diffuse Mesotheliom der Hodenhüllen. Bericht über einen Fall mit immunhistochemischer Auswertung. Pathologe 9:55–58

    Google Scholar 

  • Antman K, Cohen S, Dimitrov NV, Green M, Muggia F (1984) Malignant mesothelioma of the tunica vaginalis testis. J Clin Oncol 2:447–451

    Google Scholar 

  • Arlen M, Grabstald H, Whitmore WF (1969) Malignant tumors of the spermatic cord. Cancer 23:525–532

    Google Scholar 

  • Bailey GN, Willis RA, Wilson JV (1955) A case of adenocarcinoma of the appendix testis. J Pathol Bacteriol 69:326–328

    Google Scholar 

  • Bàrbera V, Rubino M (1957) Papillary mesothelioma of the tunica vaginalis. Cancer 10:183–189

    Google Scholar 

  • Bolen JW, Hammar SP, McNutt MA (1986) Reactive and neoplastic serosal tissue. A light-microscopic, ultrastructural, and immunocytochemical study. Am J Surg Pathol 10:34–47

    Google Scholar 

  • Cartwright LE, Steinman HK (1987) Malignant papillary mesothelioma of the tunica vaginalis testis: Cutaneous metastases showing pagetoid epidermal invasion. J Am Acad Dermatol 17:887–890

    Google Scholar 

  • Chassaigne JP, Voglimacci (1965) Mésothéliome malin de la vaginale testiculaire. Bordeaux Chir 2:81–82

    Google Scholar 

  • Chen KTK, Arhelger RB, Flam MS, Hanson JH (1982) Malignant mesothelioma of tunica vaginalis testis. Urology 20:316–319

    Google Scholar 

  • Dietemann-Molard A, Warier A, Pujol JL, Wihlm JM, Pauli G (1987) Métastases pleurales et médiastinales d'un mésothélioma malin de la membrane vaginale testiculaire. Rev Mal Resp 4:319–321

    Google Scholar 

  • Donna A, Betta PG, Bellingeri D, Marchesini A (1986) New marker for mesothelioma: an immunoperoxidase study. J Clin Pathol 39:961–968

    Google Scholar 

  • Dressler W, Permanetter W, Peters HP, Wieland WF (1988) Malignes mesotheliom der tunica vaginalis testis. Pathologe 9:318–321

    Google Scholar 

  • Dümont R, Etcheverry M, Lange D (1963) Mésothéliome malin de la vaginale testiculaire. J Urol Néphròl 69:528–530

    Google Scholar 

  • Ehya H (1985) Cytology of mesothelioma of the tunica vaginalis metastatic to the lung. Acta Cytol 29:79–84

    Google Scholar 

  • Eimoto T, Inoue I (1977) Malignant fibrous mesothelioma of the tunica vaginalis. A histologic and ultrastructural study. Cancer 39:2059–2066

    Google Scholar 

  • Enzinger FM, Weiss SW (1983) Soft tissue tumors. St Louis: C.V Mosby Company

    Google Scholar 

  • Fishelovitch J, Meiraz D, Keinan Z, Green I (1975) Malignant mesothelioma of the testicular tunica vaginalis. Br J Urol 47:208

    Google Scholar 

  • Fitzmaurice H, Hotiana MZ, Crucioli V (1987) Malignant mesothelioma of the tunica vaginalis testis. Br J Urol 60:184

    Google Scholar 

  • Fligiel Z, Kaneko M (1976) Malignant mesothelioma of the tunica vaginalis propria testis in a patient with asbestos exposure. A case report. Cancer 37:1478–1484

    Google Scholar 

  • Foot CN (1949) Testicular tumors. N Y J Med 49:284–286

    Google Scholar 

  • Galian P, Arvis G, Aboulker P (1969) Les mésothéliomas malins de la vaginale testiculaire. Étude anatomo-clinique d'un cas - Problèmes d'interprétation. Ann Urol 3:219–223

    Google Scholar 

  • Hamvasi GY, Konyár É, Romics I (1977) Über das Mesotheliom der Tunica Vaginalis. Acta Chirurgica Academiae Scientiarum Hungaricae 18:305–310

    Google Scholar 

  • Hollands MJ, Dottori V, Nash AG (1982) Malignant mesothelioma of the tunica vaginalis testis. Fur Urol 8:121–122

    Google Scholar 

  • Jaffe J, Roth JA, Carter H (1978) Malignant papillary mesothelioma of tunica vaginalis testis. Urology 11:647–650

    Google Scholar 

  • Japko L, Horta AA, Schreiber K, Mitsudo S, Karwa GL, Singh G, Koss LG (1982) Malignant mesothelioma of the tunica vaginalis testis: Report of first case with preoperative diagnosis. Cancer 49:119–127

    Google Scholar 

  • Johnson DE, Fuerst DE, Gallager SH (1973) Mesothelioma of the tunica vaginalis. South Med J 66:1295–1297

    Google Scholar 

  • Jones JSP, Lund C, Planteydt HT (1985) Colour atlas of mesothelioma. MTP Press Limited, Falcon House, Lancaster, England

    Google Scholar 

  • Karunaharan T (1986) Malignant mesothelioma of the tunica vaginalis in an asbestos worker. J R Coll Surg Eding 31:253–254

    Google Scholar 

  • Kasdon EJ (1969) Malignant mesothelioma of the tunica vaginalis propria testis. Report of two cases. Cancer 23:1144–1150

    Google Scholar 

  • Khan AR, Min A, Chai SW, Englander LS (1984) Biphasic malignant mesothelioma (malignant adenomatoid tumor) of the paratesticular tissue. Urology 24:82–84

    Google Scholar 

  • Kossow AS, McCann LS (1981) Malignant mesothelioma of the testicular tunic. J Urol 126:272–274

    Google Scholar 

  • Kozlowski H, Zoltowska A (1968) Mesothelioma of spermatic cord. A case report. Neoplasma (Bratislawa) 15:97–100

    Google Scholar 

  • Linn R, Moskovitz B, Bolkier M, Munichor M, Levin DR (1988) Paratesticular papillary mesothelioma. Urol Int 43:60–61

    Google Scholar 

  • McCaughey EWT, Al-Jabi M (1986) Differentiation of serosal hyperplasia and neoplasia in biopsies. In: Summers SC, Rosen PP, Fechner RE (eds) Pathology annual, part one. New York: Appleton-Century Crofts, pp 271–293

    Google Scholar 

  • McDonald ER, Sago AL, Novicki DE, Bagnall JW (1983) Paratesticular mesotheliomas. J Urol 130:360–361

    Google Scholar 

  • Mikuz G, Höpfel-Kreiner I (1982) Papillary mesothelioma of the tunica vaginalis propria testis. Case report and ultrastructural study. Virchows Arch [A] 396:231–238

    Google Scholar 

  • Mostofi FK, Price EB (1973) Tumours of the male genital system. AFIP, Washington DC

    Google Scholar 

  • Petersen RO (1986) Urologic Pathology. J.B. Lippincott Company Philadelphia

    Google Scholar 

  • Pfaltz M, Odermatt B, Christen B, Rüttner JR (1987) Immunohistochemistry in the diagnosis of malignant mesothelioma. Virchows Arch [A] 411:387–393

    Google Scholar 

  • Pizzolato P, Lamberty J (1976) Mesothelioma of spermatic cord. Electron microscopic and histochemical characteristics of its mucopolysaccharides. Urology 8:403–408

    Google Scholar 

  • Poissonnet M (1962) Contribution a I'étude des tumeurs de la vaginale testiculaire et du tractus épididymo-déférentiel. Thése, Paris, no 519

    Google Scholar 

  • Pugh RCB (1976) Pathology of the testis. Blackwell Scientific Publications, Oxford London Edinburgh Melbourne

    Google Scholar 

  • Reynolds CL (1958) Multiple mesotheliomas of the hydrocele sac: A case report. J Urol 79:134–137

    Google Scholar 

  • Riddell RH, Goodman MJ, Moossa AR (1981) Peritoneal malignant mesothelioma in a patient with recurrent peritonitis. Cancer 48:134–139

    Google Scholar 

  • Rosai J, Delmer LP (1975) Nodular mesothelial hyperplasia in hernia sacs. A benign reactive condition simulating a neoplasic process. Cancer 35:165–175

    Google Scholar 

  • Schou S, Andersen OP, Krarup K (1984) Malignant mesothelioma in the tunica vaginalis of the testis. Ugeskr Laeger 146:96–197

    Google Scholar 

  • Stein N, Henkes D (1986) Mesothelioma of the testicle in a child. J Urol 135:794

    Google Scholar 

  • Strickler JG, Herndier BC, Rouse RV (1987) Immunohistochemical staining in malignant mesotheliomas. Am J Clin Pathol 88:610–614

    Google Scholar 

  • Söderström J, Liedberg CF (1966) Malignant “adenomatoid” tumour of the epididymis. Acta Pathol Microbiol Scand 67:165–168

    Google Scholar 

  • Talerman A, Roth LM (1986) Pathology of the testis and its adnexa. Churchill Livingstone, New York Edinburgh London Melbourne

  • Tang CK, Gray GF, Keuhnelian JG (1976) Malignant peritoneal mesothelioma in an inguinal hernia sac. Cancer 37:1887–1890

    Google Scholar 

  • Vakalikos I, Destouni E, Valassis K, Eftichiadou C, Charalambopoulos A, Salem N (1985) Malignant mesothelioma of testicular tunica. J Surg Oncol 29:264

    Google Scholar 

  • Van Der Rhee HJ, Van Vloten WA, Scheffer E, Zwartendijk J (1983) Cutaneous manifestations of malignant mesothelioma of the tunica vaginalis testis. J Cutan Pathol 10:213–216

    Google Scholar 

  • Williams G, Banerjee R (1969) Paratesticular tumours. Br J Urol 41:332–339

    Google Scholar 

  • Yamanishi T, Wakisaka M, Ito H, Matsuzaki O, Nagao K, Schimazaki J (1984) Malignant mesothelioma of the tunica vaginalis testis. Eur Urol 10:207–209

    Google Scholar 

  • Young RH, Scully RE (1986) Testicular and paratesticular tumors and tumor-like lesions of ovarian common epithelial and Müllerian types. Am J Clin Pathol 86:146–152

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grove, A., Jensen, M.L. & Donna, A. Mesotheliomas of the tunica vaginalis testis and hernial sacs. Vichows Archiv A Pathol Anat 415, 283–292 (1989). https://doi.org/10.1007/BF00724916

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00724916

Key words

Navigation