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Extracellular and cerebrospinal fluids

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Journal of Inherited Metabolic Disease

Summary

The mechanism of formation of extracellular fluid is first described, followed by an explanation of the relation between osmotic force, reflection coefficient and molecular size. The possible mechanism of brain extracellular fluid formation is then proposed in relation to the restriction offered by the blood-brain barrier.

The functions and compositions of cerebrospinal fluid (CSF) are then described followed by sections on the process of formation of CSF, the nonelectrolytes and proteins in CSF, the drainage mechanisms and protein synthesis by the choroid plexus.

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Authors and Affiliations

  1. Sherrington School of Physiology, United Medical and Dental Schools, St. Thomas's Hospital, SE1 7EH, London, UK

    M. B. Segal

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Segal, M.B. Extracellular and cerebrospinal fluids. J Inherit Metab Dis 16, 617–638 (1993). https://doi.org/10.1007/BF00711896

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