Summary
Three new cases of sclerosing stromal tumor of the ovary have been studied by hormonal, immunohistochemical and electron microscopic analysis. The results confirm that this tumor may have hormonal activity. Ultrastructural study shows findings different from those previously reported. The authors propose an origin from the ovarian stroma with luteinization of stromal tumor cells.
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References
Amin HK, Okagaki T, Richart RM (1971) Thecoma of the ovary. An ultrastructural study. Cancer 27:438–446
Bjersing L, Frankendal B, Ångström T (1973) Studies on a feminizing ovarian mesenchymoma (granulosa cell tumor). I. Aspiration biopsy cytology, histology and ultrastructure. Cancer 32:1360–1369
Chalvardjian A, Scully RE (1973) Sclerosing stromal tumors of the ovary. Cancer 31:664–670
Damjanov I, Drobnjak P, Grizelj V, Longhino N (1975) Sclerosing stromal tumor of the ovary. A hormonal and ultrastructural analysis. Obstet Gynecol 45:675–679
Garcia-Bunuel R, Brandes D (1976) Luteoma of pregnancy: ultrastructural features. Hum Pathol 7:205–214
Gee DC, Russell P (1979) Sclerosing stromal tumours of the ovary. Histopathology 3:367–376
Holtz F, Hart WR (1982) Krukenberg tumors of the ovary. A clinicopathologic analysis of 27 cases. Cancer 50:2438–2447
Ishida T, Okagaki T, Tagatz GE, Jacobson ME, Doe RP (1977) Lipid cell tumor of the ovary: an ultrastructural study. Cancer 40:234–243
Kalstone CE, Jaffe RB, Abell MR (1969) Massive edema of the ovary simulating fibroma. Obstet Gynecol 34:564–571
Kempson R (1968) Ultrastructure of ovarian stromal cell tumors. Sertoli-Leydig cell tumor and lipid cell tumor. Arch Pathol 86:492–507
Lack EE, Perez-Atayde AR, Murthy ASK, Goldstein DP, Crigler JF, Vawter GF (1981) Granulosa theca cell tumors in premenarchal girls: a clinical and pathologic study of ten cases. Cancer 48:1846–1854
Majmudar B, Kapernick PS, Phillips RS (1978) Ovarian myxoma. Hum Pathol 9:723–725
Murad TM, Mancini R, George J (1973) Ultrastructure of a virilizing ovarian Sertoli-Leydig cell. Tumor with familial incidence. Cancer 31:1440–1450
Paradisi R, Venturoli S, Martinelli G, Serra L, Govoni E, Fabbri R, Flamigni C (1982) In vivo endocrine studies and morphological features in a case of hilus cell tumor in mesovarium. Gynecol Obstet Invest 14:184–194
Pelusi G, Busacchi P, Moretti B (1979) Aspetti endocrini dell'adenocarcinoma, dell'iperplasia adenomatosa e dell'iperplasia ghiandolare semplice dell'endometrio. Minerva Ginecologica 31:747–760
Pileri S, Serra L, Martinelli G (1980) The use of pronase enhances sensitivity of the PAP method in the detection of intracytoplasmatic immunoglobulins. Bas Appl Histochem 241:203–207
Ramzy I (1976) Signet-ring stromal tumor of ovary. Histochemical, light, and electron microscopic study. Cancer 38:166–172
Ramzy I, Bos C (1976) Sertoli cell tumors of ovary. Light microscopic and ultrastructural study with histogenetic considerations. Cancer 38:2447–2456
Roth LM, Deaton RL, Sternberg WH (1979) Massive ovarian edema. A clinicopathologic study of five cases including ultrastructural observations and review of the literature. Am J Surg Pathol 3:11–21
Roth LM, Nicholas TR, Ehrlich CE (1979) Juvenile granulosa cell tumor. A clinicopathologic study of three cases with ultrastructural observations. Cancer 44:2194–2205
Scully RE (1977) Ovarian tumors. A review. Am J Pathol 87:686–720
Tavassoli FA, Norris HJ (1980) Sertoli tumors of the ovary. A clinicopathologic study of 28 cases with ultrastructural observations. Cancer 46:2281–2297
Toker C (1968) Theca cell tumor. An ultrastructural study. Am J Obstet Gynecol 15:779–784
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Martinelli, G., Govoni, E., Pileri, S. et al. Sclerosing stromal tumor of the ovary. Vichows Archiv A Pathol Anat 402, 155–161 (1983). https://doi.org/10.1007/BF00695057
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DOI: https://doi.org/10.1007/BF00695057