Summary
Lafora-like bodies in an 8-year-old cat were studied light and electron microscopically and histochemically. In addition to Lafora-like bodies composed of branching filaments, glycogen granules and electron-dense materials, abnormal accumulations of glycogen granules attracted attention. The most remarkable features were the developmental processes of the branching filaments originating directly from glycogen granules. Lafora-like bodies in the present study showed ultrastructural, histochemical, and enzymatic similarities to those described in the previous reports in Lafora's disease, glycogenosis and other cases. From these results, a certain disturbance of the glycogen metabolism is considered to be probably related to the productive mechanism of Lafora-like bodies.
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Suzuki, Y., Kamiya, S., Ohta, K. et al. Lafora-like bodies in a cat. Acta Neuropathol 48, 55–58 (1979). https://doi.org/10.1007/BF00691791
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DOI: https://doi.org/10.1007/BF00691791