Summary
The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy. Straight tubules and twisted tubules were observed in both the cortical and subcortical neurofibrillary tangles. Most tubules appeared separately in each neuron but a few straight tubules were mixed with the twisted tubules in the cortical tangles. The implication and possible significance of this findings are discussed.
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Yagishita, S., Itoh, Y., Amano, N. et al. Ultrastructure of neurofibrillary tangles in progressive supranuclear palsy. Acta Neuropathol 48, 27–30 (1979). https://doi.org/10.1007/BF00691787
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DOI: https://doi.org/10.1007/BF00691787