Summary
This research attempts to present the histochemically distribution of mucopolysaccharides and glycoproteins in the reactive structures of 30 tumors histologically identified as astrocytoma and as multiform glioblastoma. Generally the tumoral astrocytes appeared as elements forming glycoprotein and neutral mucopolysaccharides and to a lesser extent, acid mucopolysaccharides. The amino sugars, irrespective of whether they establish connections with uronic or sialic acids, with esters of sulfuric or phosphoric acids, prevailingly occur in differentiated and mature tumoral cells. The vascular connective stroma contains larger amounts of mucopolysaccharides than the tumoral parenchyma. Therefore the same differences in the histochemistry of mucopolysaccharides in astrocytoma and in multiform glioblastoma are evident.
Zusammenfassung
Diese Arbeit versucht die histochemische Verteilung von Mucopolysacchariden und Glykoproteinen in den reaktiven Strukturen von 30 Tumoren, die histologisch als Astrocytome und als multiforme Glioblastome erkannt wurden, zu beschreiben. Gewöhnlich erscheinen die tumoralen Astrocyten als Elemente, die Glykoproteine, neutrale Mucopolysaccharide und selten saure Mucopolysaccharide produzieren. Der Amino-Zucker, gleichgültig ob er sich mit Uron-oder Speichel-Säuren, mit Estern der Schwefel-oder Phosphor-Säure verbindet, erscheint gewöhnlich in differenzierten und erwachsenen Tumorzellen. Das vasculäre Bindegewebsstroma enthält eine größere Menge von Mucopolysacchariden als das Tumorparenchym. Man kann daher den Schluß ableiten, daß einige Unterschiede in der histochemischen Struktur der Mucopolysaccharide in Astrocytomen und Glioblastomata multiformia nachweisbar sind.
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Arseni, C., Carp, N., Mestes, E. et al. Histochemistry of mucopolysaccharides in brain tumors. Acta Neuropathol 7, 275–284 (1967). https://doi.org/10.1007/BF00686378
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DOI: https://doi.org/10.1007/BF00686378