Skip to main content
SpringerLink
Log in

DNA content of meningiomas

  • Original Works
  • Published:
Acta Neuropathologica Aims and scope Submit manuscript

Summary

Flow cytometric DNA analysis was carried out in 35 meningiomas. Thirty-three had diploid stem lines while two were aneuploid having a triploid DNA mode. Both aneuploid meningiomas were grossly huge nodular tumours and one had malignant histologic features.

Flow cytometry in meningiomas is a rapid means of determining the DNA modes and adds objective information to microscopy. Appropriate cases may be selected for further cytogenetic studies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Adler, C. P., Hartz, A., Sandritter, W.: Form and structure of cell nuclei in growing and hypertrophied human hearts. Beitr. Pathol.161, 342–362 (1977)

    Google Scholar 

  • Aktin, N. B., Mattinson, G., Baker, M. C.: A comparison of the DNA content and chromosome number of fifty human tumours. Br. J. Cancer20, 84–101 (1966)

    Google Scholar 

  • Frederiksen, P., Reske-Nielsen, E., Bichel, P.: Flow cytometry in tumours of the brain. Acta Neuropathol. (Berl.)41, 179–183 (1978)

    Google Scholar 

  • Jellinger, K., Slowik, F.: Histological subtypes and prognostic problems in meningiomas. J. Neurol.208, 279–298 (1975)

    Google Scholar 

  • Jörgenshaus, W.: Zytophotometrische Untersuchungen über die DNS-Verteilung in menschlichen Meningomen. Inaug.-Diss., Univ. Köln 1978

  • Kraemer, P. M., Deaven, L. L., Crissman, H. A., Van Dilla, M. A.: CNA constancy dispite variability in chromosome number. In: Advances in cell and molecular biology. Vol. 2, pp. 47–108. New York, London: Academic Press 1972

    Google Scholar 

  • Mark, J.: Chromosomal patterns in human meningiomas. Eur. J. Cancer6, 489–498 (1970)

    Google Scholar 

  • Mark, J.: The fluorescence karyotypes of three human meningiomas with hyperdiploid-hypotriploid stemlines. Acta Neuropathol. (Berl.)25, 46–53 (1973)

    Google Scholar 

  • Russell, D. S., Rubinstein, L. J.: Pathology of tumours of the nervous system. 4th ed., pp. 65–91. London: Arnold 1977

    Google Scholar 

  • Skullerud, K., Löken, A. C.: The prognosis in meningiomas. Acta Neuropathol. (Berl.)29, 337–344 (1974)

    Google Scholar 

  • Singer, H., Zang, K. D.: Cytologische und cytogenetische Untersuchungen an Hirntumoren. Humangenetik9, 172–184 (1970)

    Google Scholar 

  • Zankl, H., Singer, H., Zang, K. D.: Cytological and cytogenetical studies on brain tumours. Humangenetik11, 253–257 (1971)

    Google Scholar 

  • Zülch, K. J.: Atlas of gross neurosurgical pathology. pp. 31–34. Berlin, Heidelberg, New York: Springer 1975

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neuropathology, Aarhus University School of Medicine, DK-8000, Aarhus, Denmark

    P. Frederiksen & E. Reske-Nielsen

  2. Institute of Cancer Research (sponsored by the Danish Cancer Society), Radiumstationen, DK-8000, Aarhus, Denmark

    P. Bichel

Authors
  1. P. Frederiksen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. Reske-Nielsen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Bichel
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Frederiksen, P., Reske-Nielsen, E. & Bichel, P. DNA content of meningiomas. Acta Neuropathol 46, 65–68 (1979). https://doi.org/10.1007/BF00684806

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00684806

Key words

Search

Navigation