Summary
Primary actinomycoma of the third ventricle has been reported to be a very rare form of central nervous system actinomycosis. Others have demonstrated actinomycotic-like colonies in colloid cysts of the third ventricle. We have confirmed these structures (HLS) in five colloid cysts and have demonstrated by various histochemical stains that they consist of desoxyribose nucleic acid, basic protein and phospholipid. Ultrastructurally, they consist of amorphous to granular electron dense material, probably deposited on a lamellar substructure. On the basis of the available information, we believe that the lesions, previously reported as primary actinomycomas, are actually colloid cysts containing degenerative HLS. The possible origin of the hyphal-like structures is discussed.
Similar content being viewed by others
References
Bollinger, V. O.: Über primäre Actinomykose des Gehirns beim Menschen. Münch. med. Wschr.34, 789–792 (1887)
Bolton, C. F., Ashenhurst, E. M.: Actinomycosis of the brain. Canad. med. Ass. J.90, 922–928 (1964)
Clark, G., Powers, J. M.: A consistent phosphotungstic acid hematoxylin stain for glial fibers. Stain Technol.51, 227–229 (1976)
Dandy, W. E.: Benign tumors in the third ventricle of the brain, pp. 1–37. Springfield, Ill.: Ch. C. Thomas 1933
Dublin, W. B.: Fundamentals of neuropathology, p. 116. Springfield, Ill.: Ch. C. Thomas 1967
Fetter, B. F., Klintworth, G. K., Hendry, W. S.: Mycoses of the central nervous system, pp. 18–21. Baltimore, Maryland: Williams and Wilkins 1967
Garvin, A. J., Spicer, S. S., Paremly, R. T., Munster, A. M.: Immunohistochemical demonstration of IgG in Reed-Sternberg and other cells in Hodgkin's disease. J. exp. Med.139, 1077–1083 (1974)
Hallervorden, J.: Ein Aktinomykom im 3. Ventrikel. Arch. Psychiat. Nervenkr.95, 527–536 (1931)
Landolt-Weber, U. M.: Ultrastruktur einer Kolloidcyste des dritten Ventrikels. Acta neuropath. (Berl.)26, 59–70 (1973)
Mosberg, W. H., Jr., Blackwood W.: Mucus-secreting cells in colloid cysts of the third ventricle. J. Neuropath. exp. Neurol.13, 417–426 (1954)
Orr, T. G.: Actinomycoma of the third ventricle, probably primary. J. Amer. med. Ass.127, 757 (1945)
Puchtler, H., Sweat, F.: A combined hemoglobin-hemosiderin stain. Arch. Path.75, 588–590 (1963)
Roque, A. L.: Chromotrope aniline blue method of staining Mallory bodies of Laennec's cirrhosis. Lab. Invest.2, 15–21 (1953)
Russell D. S., Rubinstein, L. J.: Pathology of tumors of the nervous system, pp. 120–122; 166–168, Baltimore, Maryland: Williams and Wilkins 1971
Schwartz, J., Hansen, J. L.: Paraphysial cyst of the third ventricle. Arch. Path.52, 280–287 (1951)
Sternberg, C.: Zur Kenntnis der Aktinomykose des Gehirns. Z. Hyg. Infektkr.113, 151–159 (1931)
Stevens, H.: Actinomycosis of the nervous system. Neurology (Minneap.)3, 761–772 (1953)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Powers, J.M., Dodds, H.M. Primary actinomycoma of the third ventricle—The colloid cyst. Acta Neuropathol 37, 21–26 (1977). https://doi.org/10.1007/BF00684535
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00684535