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A method for increasing the frequency response of voltage clamped myelinated nerve fibres

  • Excitable Tissues and Central Nervous Physiology
  • Instruments and Techniques
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Abstract

In voltage clamp experiments on myelinated nerve fibres the time resolution of the current measurement is limited by the low-pass characteristics of the internodes. We increased the corner frequency of the current passing internode by grounding one half of this internode externally. Using a simplified equivalent circuit we calculated an increase in the bandwidth of the internode by a factor of about 6. Consequently, the peak value of the recorded capacity current increased while its duration was considerably shortened.

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Authors and Affiliations

  1. Physiologisches Institut der Universität Kiel, Olshausenstr. 40/60, D-2300, Kiel, Germany

    E. Koppenhöfer & H. Schumann

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  1. E. Koppenhöfer
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  2. H. Schumann
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Koppenhöfer, E., Schumann, H. A method for increasing the frequency response of voltage clamped myelinated nerve fibres. Pflugers Arch. 390, 288–289 (1981). https://doi.org/10.1007/BF00658278

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  • DOI: https://doi.org/10.1007/BF00658278

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