Summary
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1.
The vigilance states (waking, slow wave sleep (SWS) and paradoxical sleep (PS)), motor activity, food intake and water consumption were continuously recorded by telemetry in unrestrained rats. The animals were maintained for 2 days under 12-h light−12-h dark conditions (LD 12∶12). Subsequently, the photoperiod was gradually extended by 1 h/day from 12 to 20 h, and restored to the original length for the last 2 days. In one group of animals the extension of the photoperiod was obtained by phase-advancing light-onset (La-group), in the other by phase-delaying dark-onset (Dd-group).
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2.
During the LD 12∶12 control period, sleep, motor activity and food intake exhibited an asymmetric daily distribution. The percentages (Fig. 2) and episode durations (Fig. 4) of total sleep (TS) and slow wave sleep (SWS) were highest at the beginning of the light-phase and then exhibited a decreasing trend. The corresponding values for PS showed a slight increasing trend during the light-phase. A marked increasing trend during the light-phase was seen for PS expressed as the percentage of TS. Motor activity (Fig. 3) was minimal and food intake (Fig. 6) absent during the first half of the light-phase, increasing gradually during the second half. The daily minimum of sleep and the daily maximum of motor activity were situated at the end of the dark-phase.
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3.
During the extension of the photoperiod the daily period of high activity and waking was shortened and remained largely restricted to the dark-phase (Figs. 7–9). Motor activity and food intake were more restricted to the dark-phase in the La-group than in the Dd-group. Throughout the experiment, the percentage of PS relative to TS remained lower at the beginning of the light-phase than towards its end, whereas the values for TS and SWS tended to show an inverse relationship (Figs. 9–11). After restoration of the original LD 12∶12 condition, the altered daily patterns of sleep and motor activity tended to persist.
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4.
The daily pattern of sleep in the rat with the predominance of SWS in the early part of the rest period, and of PS in the late part, is strikingly similar to the distribution of sleep states in man. The difference in the daily rhythms of SWS and PS may reflect a phase-difference of two separate, and partly independent, circadian oscillators.
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References
Aschoff, J.: Aktivitätsmuster der Tagesperiodik. Naturwissenschaften44, 361–367 (1957)
Aschoff, J., Figala, J., Pöppel, E.: Circadian rhythms of locomotor activity in the golden hamster (Mesocricetus auratus) measured with two different techniques. J. comp. physiol. Psychol.85, 20–28 (1973)
Aschoff, J., Gerecke, U., Kureck, A., Pohl, H., Rieger, P., v. Saint-Paul, U., Wever, R.: Interdependent parameters of circadian activity rhythms in birds and man. In: Biochronometry (ed. M. Menaker), pp. 3–29. Washington: National Academy of Sciences 1971
Aschoff, J., Meyer-Lohmann, J.: Die Aktivitätsperiodik von Nagern im künstlichen 24-Stunden-Tag mit 0 Stunden Lichtzeit. Z. vergl. Physiol.37, 107–117 (1955)
Borbély, A.A.: Circadian rhythm of vigilance in rats: modulation by short light-dark cycles. Neuroscience Letters1, 67–71 (1975)
Borbély, A.A.: Sleep and motor activity of the rat during ultra-short light-dark cycles. Brain Res.114, 305–317 (1976)
Borbély, A.A.: Sleep in the rat during food deprivation and subsequent restitution of food. Brain Res.124, 457–471 (1977)
Borbély, A.A.: Effects of light on sleep and activity rhythms. Progr. Neurobiol., in press (1978)
Borbély, A.A., Huston, J.P.: Effects of two-hour light-dark cycles on feeding, drinking and motor activity of the rat. Physiol. Behav.13, 795–802 (1974)
Borbély, A.A., Huston, J.P., Waser, P.G.: Control of sleep states in the rat by short light-dark cycles. Brain Res.95, 89–101 (1975)
Carskadon, M.A., Dement, W.C.: Sleep studies on a 90-minute day. Electroenceph. clin. Neurophysiol.39, 145–155 (1975)
Colvin, G.B., Whitmoyer, D.I., Lisk, R.D., Walter, D.O., Sawyer, C.H.: Changes in sleep-wakefulness in female rats during circadian and estrous cycles. Brain Res.7, 173–181 (1968)
Colvin, G.B., Whitmoyer, D.I., Sawyer, C.H.: Circadian sleep-wakefulness patterns in rats after ovariectomy and treatment with estrogen. Exp. Neurol.25, 616–625 (1969)
Daan, S., Pittendrigh, C.S.: A functional analysis of circadian pacemakers in nocturnal rodents. II. The variability of phase response curves. J. comp. Physiol.106, 253–266 (1976a)
Daan, S., Pittendrigh, C.S.: A functional analysis of circadian pacemakers in nocturnal rodents. III. Heavy water and constant light: homeostasis of frequency? J. comp. Physiol.106, 267–290 (1976b)
DeCoursey, P.: Phase control of activity in a rodent. Cold Spr. Harb. Symp. quant. Biol.25, 49–55 (1960a)
DeCoursey, P.: Daily light sensitivity in a rodent. Science131, 33–35 (1960b)
Feinberg, I.: Functional implications of changes in sleep physiology with age. In: Neurobiology of aging (eds. R.D. Terry, S. Gershon), pp. 23–41. New York: Raven Press 1976
Karacan, I., Williams, R.L., Finley, W.W., Hursch, C.J.: The effects of naps on nocturnal sleep: influence on the need for stage-1 REM and stage 4 sleep. Biol. Psychiatry2, 391–399 (1970)
Kleitman, N.: Sleep and wakefulness. Chicago: The University of Chicago Press 1963
Lienert, G.A.: Verteilungsfreie Methoden in der Biostatistik. Band I. Meisenheim am Glan: Verlag Anton Hain 1973
Mitler, M.M., Lund, R., Sokolove, P.G., Pittendrigh, C.S., Dement, W.C.: Sleep and activity rhythms in mice: a description of circadian patterns and unexpected disruptions in sleep. Brain Res.131, 129–146 (1977)
Neuhaus, H.U., Borbély, A.A.: Sleep telemetry in the rat: II. Automatic identification and recording of vigilance states. Electroenceph. clin. Neurophysiol.44, 115–119 (1978)
Pittendrigh, C.S., Daan, S.: A functional analysis of circadian pacemakers in nocturnal rodents. I. The stability and lability of spontaneous frequency. J. comp. Physiol.106, 223–252 (1976a)
Pittendrigh, C.S., Daan, S.: A functional analysis of circadian pacemakers in nocturnal rodents. IV. Entrainment: pacemaker as clock. J. comp. Physiol.106, 291–331 (1976b)
Pittendrigh, C.S., Daan, S.: A functional analysis of circadian pacemakers in nocturnal rodents. V. Pacemaker structure: a clock for all seasons. J. comp. Physiol.106, 333–355 (1976c)
Rosenberg, R.S., Bergmann, B.M., Rechtschaffen, A.: Variations in slow wave activity during sleep in the rat. Physiol. Behav.17, 931–938 (1976)
Ruedin, P., Bisang, J., Waser, P.G., Borbély, A.A.: Sleep telemetry in the rat: I. A miniaturized FM-AM transmitter for EEG and EMG. Electroenceph. clin. Neurophysiol.44, 112–114 (1978)
Tribukait, B.: Die Aktivitätsperiodik der weißen Maus im Kunsttag von 16–29 Stunden Länge. Z. vergl. Physiol.38, 479–490 (1956)
Verdone, P.: Sleep satiation: extended sleep in normal subjects. Electroenceph. clin. Neurophysiol.24, 417–423 (1968)
Webb, W.B., Agnew, H.W.: Stage 4 sleep: influence of time course variables. Science174, 1354–1356 (1971)
Webb, W.B., Agnew, H.W.: Sleep and waking in a time-free environment. Aerospace Med.45, 617–622 (1974)
Webb, W.B., Agnew, H.W., Sternthal, H.: Sleep during the early morning. Psychon. Sci.6, 277–278 (1966)
Webb, W.B., Friedmann, J.K.: Some temporal characteristics of paradoxical (LVF) sleep occurrence in the rat. Electroenceph. clin. Neurophysiol.30, 453–456 (1971)
Weitzman, E.D., Nogeire, C, Perlow, M., Fukushima, D., Sassin, J., McGregor, P., Gallagher, T.F., Hellman, L.: Effects of a prolonged 3-hour sleep-wake cycle on sleep stages, plasma cortisol, growth hormone and body temperature in man. J. clin. Endocr.38, 1018–1030 (1974)
Zwahlen, R.: Die lokomotorische Aktivität des Eichhörnchens (Sciurus vulgaris). Oecologia (Berl.)22, 79–98 (1975)
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The study was supported by the Swiss National Science Foundation, grant nr. 3.624-0.75 and the Hartmann-Mueller Foundation for Medical Research. We thank Ms. Maiya Loepfe-Hinkkanen for valuable help with the experiments and data analysis, Ms. Margrit Donatz for typing, and Dr. J.P. Huston for comments on the manuscript.
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Borbély, A.A., Neuhaus, H.U. Daily pattern of sleep, motor activity and feeding in the rat: Effects of regular and gradually extended photoperiods. J. Comp. Physiol. 124, 1–14 (1978). https://doi.org/10.1007/BF00656386
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DOI: https://doi.org/10.1007/BF00656386