Summary
MRI was performed on seven patients with acute optic neuritis, using two sequences which suppress the signal from orbital fat: frequency-selective fat-saturation and inversion recovery with a short inversion time. Lesions were seen on both sequences in all the symptomatic optic nerves studied.
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References
Matthews WB (1991) McAlpine's multiple sclerosis, 2nd edn. Churchill Livingstone, Edinburgh
Francis DA, Compston DAS, Batchelor JR, McDonald WI (1987) A reassessment of the risk of multiple sclerosis developing in patients with optic neuritis after extended follow up. J Neurol Neurosurg Psychiatry 50: 758–765
Halliday AM (1982) Evoked potentials in clinical testing. Churchill Livingstone, Edinburgh
Miller DH, Newton MR, van der Poel JC, du Boulay EPGH, Halliday AM, Kendall BE, Johnson G, Mac Manus DG, Moseley IF, McDonald WI (1988) Magnetic resonance imaging of the optic nerve in optic neuritis. Neurology 38: 175–179
Simon J, Szumowski J, Totterman S, et al (1988). Fat-suppression MR imaging of the orbit. AJNR 9: 961–968
Compston DAS, Batchelor JR, Earl CJ, McDonald WI (1978) Factors influencing the risk of multiple sclerosis developing in patients with optic neuritis. Brain 101: 495–511
Miller DH, Rudge P, Johnson G, Kendall BE, Mac Manus DG, Moseley IF, Barnes D, McDonald WI (1988) Serial gadoliniumenhanced magnetic resonance imaging in multiple sclerosis. Brain 111: 927–939
Thompson AJ, Kermode AG, Wicks D, Mac Manus DG, Kendall BE, Kingsley DPE, McDonald WI (1991) Major differences in the dynamics of primary and secondary progressive multiple sclerosis. Ann Neurol 29: 53–62
Harris JO, Frank JA, Patronas N, McFarlin DE, McFarland HF (1991) Serial gadolinium-enhanced magnetic resonance imaging scans in patients with early, relapsing-remitting multiple sclerosis: implications for clinical trials and natural history. Ann Neurol 9: 548–555
Katz J, Taubenberger J, Raine C, et al (1990) Gadolinium-enhancing lesions on magnetic resonance imaging: neuropathological findings. Ann Neurol 28: 243
Youl BD, Turano G, Miller DH, Towell AD, mac Manus DG, Moore SG, Jones SJ, Barrett G, Kendall BE, Moseley JF, Tofts PS, Halliday AM, McDonald WI (1991) The pathophysiology of acute optic neuritis: an association of gadolinium leakage with clinical and electrophysiological deficits. Brain 114: 2437–2450
Barnes D, McDonald WI, Johnson G, Tofts PS, Landon DN (1987) Quantitative nuclear magnetic resonance imaging: characterisation of experimental cerebral oedema. J Neurol Neurosurg Psychiatry 50: 125–133
Barnes D, McDonald WI, Landon DN, Johnson G (1988) The characterisation of experimental gliosis by quantitative nuclear magnetic resonance imaging. Brain 111: 83–94
Hendrix LE, Kneeland JB, Haughton VM, et al (1990) MR imaging of optic nerve lesions: value of gadopentate dimeglumine and fat-suppression technique. AJNR 11: 749–754
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Miller, D.H., Mac Manus, D.G., Bartlett, P.A. et al. Detection of optic nerve lesions in optic neuritis using frequency-selective fat-saturation sequences. Neuroradiology 35, 156–158 (1993). https://doi.org/10.1007/BF00593976
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DOI: https://doi.org/10.1007/BF00593976