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Arterial cell renewal under hyperlipidemic conditions

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Summary

The renewal of arterial cells under various hyper- and normo-lipidemic conditions has been studied by 3H-thymidine autoradiography. In hyper-lipidemia the endothelium shows a greater propensity to proliferate than in normo-lipidemia, but in both conditions the smooth muscle cells of the tunica media also proliferate when the intima is injured.

Zusammenfassung

Die arterielle Zellneubildung wurde unter verschiedenen hyper- und normolipämischen Zuständen mit 3H-thymidin-autoradiographie untersucht. Bei Hyperlipämie zeigt das Endothel größere Neigung zur Proliferation als bei Normolipämie. Bei beiden Zuständen jedoch proliferieren auch die glatten Muskelzellen in der Tunica media im Zusammenhang mit Intimaverletzungen.

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Authors and Affiliations

  1. Department of Pathology, University of Umeå, Sweden

    Ove Hassler

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  1. Ove Hassler
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Hassler, O. Arterial cell renewal under hyperlipidemic conditions. Virchows Arch. Abt. A Path. Anat. 352, 26–33 (1971). https://doi.org/10.1007/BF00549760

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  • DOI: https://doi.org/10.1007/BF00549760

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