Skip to main content
Log in

Immunocytochemical evidence for the presence of somatostatin-like immunoreactivity in scattered cells of the duct system of the submandibular glands in the Monkey, Macaca irus

  • Published:
Histochemistry Aims and scope Submit manuscript

Summary

Using the indirect immunofluorescent technique with anti-somatostatin serum, the distribution of scattered cells in the duct system of submandibular glands in the Monkey, Macaca irus has been assessed. In both males and females, these cells are located only in some portions of the duct system, e.g. striated ducts and excretory ducts. No immunoreactive cells were observed in the intercalated ducts or in secretory endpieces. The lymphatic node constantly adjacent to the submandibular gland did not contain immunoreactive cells. In the parotid glands, no immunoreactive cells to antisomatostatin immuneserum were ever observed

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alumets J, Sundler F, Håkanson R (1977) Distribution, ontogeny and ultrastructure of somatostatin immunoreactive cells in the pancreas and gut. Cell Tissue Res 185:465–479

    Google Scholar 

  • Arimura A, Coy DH, Chihara M, Fernandez-Durango R, Samols E, Chihara K, Meyers CA, Schally AV (1978) Somatostatin. In: Bloom SR, Grossman MI (eds) Gut hormones. Churchill Livingstone, Edinburgh London New York, pp 437–445

    Google Scholar 

  • Buchan AMJ, Polak JM (1980) The classification of the human gastroenteropancreatic endocrine cells. Invest Cell Pathol 3:51–71

    Google Scholar 

  • Dubois MP (1978) Differentiation of immunoreactive neurosecretory cells. A review. In: Vincent JD, Kordon C (eds) Biologie cellulaire des processus neurosécrétoires hypothalamiques. CNRS, Paris, pp 701–723

    Google Scholar 

  • Dubois MP, Billard R, Breton B, Peter RE (1979) Comparative distribution of somatostatin, LH-RH, neurophysin, and α-endorphin in the rainbow trout: an immunocytochemical study. Gen Comp Endocrinol 37:220–232

    Google Scholar 

  • Elde R, Hökfelt T, Johansson O, Schultzberg M, Efendić S, Luft R (1978) Cellular localization of somatostatin. Metabolism 27 (Suppl I):1151–1159

    Google Scholar 

  • Falkmer S, Elde RP, Hellerström C, Petersson B, Efendić S, Fohlman J, Siljevall JB (1977) Some phylogenetical aspects on the occurence of somatostatin in the gastro-entero-pancreatic endocrine system. A histological and immunocytochemical study, combined with quantitative radioimmunoassays of tissue extracts. Arch Histol Jpn 40 (Suppl):99–117

    Google Scholar 

  • Falkmer S, Elde RP, Hellerström C, Petersson B (1978) Phylogenetic aspects of somatostatin in the gastroenteropancreatic (GEP) endocrine system. Metabolism 27 (Suppl 1):1193–1196

    Google Scholar 

  • Forssmann WG, Helmstaedter V, Metz J, Mühlmann G, Feurle GE (1978) Immunohistochemistry and ultrastructure of somatostatin cells with special reference to the gastroenteropancreatic (GEP) system. Metabolism 27 (Suppl 1):1179–1191

    Google Scholar 

  • Girod C (1964) Étude d'un dimorphisme sexuel de la glande sous-maxillaire du singe Macacus irus F. Cuv. CR Soc Biol (Paris) 158:752–754

    Google Scholar 

  • Girod C (1977) Apport de l'immunohistochimie à l'étude cytologique de l'adénohypophyse. Bull Assoc Anat 175:417–603

    Google Scholar 

  • Girod C, Dubois MP, Durand N (1979a) Mise en évidence, par immunofluorescence, des cellules à somatostatine dans les îlots de Langerhans chez trois espèces de Singes. CR Soc Biol (Paris) 173:542–546

    Google Scholar 

  • Girod C, Dubois MP, Durand N (1979b) Mise en évidence, par immunofluorescence, de cellules à somatostatine dans le tube digestif des singes Macacus irus, Papio hamadryas et Cercopithecus aethiops. CR Soc Biol (Paris) 173:917–921

    Google Scholar 

  • Grube D, Forssmann WG (1979) Morphology and function of the entero-endocrine cells. Horm Metab Res 11:589–606

    Google Scholar 

  • Grube D, Weber E (1980) Immunoreactivities of gastrin (G-)cells. I. Dilution-dependent staining of G-cells by antisera and non-immune sera. Histochemistry 65:223–237

    Google Scholar 

  • Hökfelt T, Efendić S, Hellerström C, Johansson O, Luft R, Arimura A (1975) Cellular localization of somatostatin in endocrine-like cells and neurons of the rat with special references to the A1-cells of the pancreatic islets and to the hypothalamus. Acta Endocrinol (Kbh) 80 (Suppl 200): 5–41

    Google Scholar 

  • Jackson IMD (1978) Extrahypothalamic and phylogenetic distribution of hypothalamic peptides. In: Reichlin S, Baldessarini RJ, Martin JB (eds) The hypothalamus. Raven Press, New York, pp 217–231

    Google Scholar 

  • King JA, Millar RP (1979) Phylogenetic and anatomical distribution of somatostatin in vertebrates. Endocrinology 105:1322–1329

    Google Scholar 

  • Kronheim S, Berelowitz M, Pimstone BL (1976) A radioimmunoassay for growth hormone release-inhibiting hormone: method and quantitative tissue distribution. Clin Endocrinol (Oxf) 5:619–630

    Google Scholar 

  • Langer M, Van Noorden S, Polak JM, Pearse AGE (1979) Peptide hormone-like immunoreactivity in the gastrointestinal tract and endocrine pancreas of eleven teleost species. Cell Tissue Res 199:493–508

    Google Scholar 

  • Lehy T, Cristina ML (1979) Ontogeny and distribution of certain endocrine cells in the human fetal large intestine. Histochemical and immunocytochemical studies. Cell Tissue Res 203:415–426

    Google Scholar 

  • McQuillan MT (1977) Somatostatin, vol. 1. Annual Research Reviews. Eden Press, Montreal

    Google Scholar 

  • Molnar J, Arimura A, Kastin AJ (1976) Presence of immunoreactive somatostatin in the salivary gland and saliva. Fed Proc 35:782 (Abstr no. 3172)

    Google Scholar 

  • Orci L, Baetens D, Ravazzola M, Malaisse-Lagae F, Amherdt M, Rufener C (1976) Somatostatin in the pancreas and the gastrointestinal tract. In: Fujita T (ed) Endocrine gut and pancreas. Elsevier Scientific, Amsterdam, pp 73–88

    Google Scholar 

  • Parsons JA, Erlandsen SL, Hegre OD, McEvoy RC, Elde RP (1976) Central and peripheral localization of somatostatin. Immunoenzyme immunocytochemical studies. J Histochem Cytochem 24:872–882

    Google Scholar 

  • Polak JM, Bloom SR (1979) The hormones of the gastrointestinal tract. In: Duthie HL, Wormsley KG (eds) Scientific basis of gastroenterology. Churchill Livingstone, Edinburgh London New York, pp 71–111

    Google Scholar 

  • Rahier J, Wallon J, Henquin JC (1980) Abundance of somatostatin cells in the human neonatal pancreas. Diabetologia 18:251–254

    Google Scholar 

  • Seino Y, Porte Djr, Smith PH (1979) Immunohistochemical localization of somatostatin-containing cells in the intestinal tract: a comparative study. Gen Comp Endocrinol 38:229–233

    Google Scholar 

  • Solcia E, Capella C, Buffa R, Usellini L, Frigerio B, Fontana P (1979) Endocrine cells of the gastrointestinal tract and related tumors. In: Ioachim HL (ed) Pathobiology annual. Raven Press, New York, pp 163–204

    Google Scholar 

  • Track NS (1980) The gastrointestinal endocrine system. CMA J 122:287–292

    Google Scholar 

  • Young JA, Van Lennep EW (1978) The morphology of salivary glands. Academic Press, London New York San Francisco, pp 1–273

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Girod, C., Dubois, M.P. & Durand, N. Immunocytochemical evidence for the presence of somatostatin-like immunoreactivity in scattered cells of the duct system of the submandibular glands in the Monkey, Macaca irus . Histochemistry 69, 137–143 (1980). https://doi.org/10.1007/BF00533130

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00533130

Keywords

Navigation