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Neuroembryogenesis in the hippocampal formation of the rat

An autoradiographic study

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The prenatal ontogeny of the hippocampus, including the anterior continuation and induseum griseum, was examined in the rat by means of tritiated thymidine autoradiography.

The neurons of the anterior continuation formed between the 16th and 18th days of embryonic development. The neurons of the induseum griseum were formed on the 16th and 17th days of gestation. The pyramidal cells of ammon's horn were formed during the 16th, 17th, 18th, and 19th days of embryogenesis but were preceded by the large interneurons of the stratum lacunosum-moleculare which formed on days 15 and 16 of embryonic life. The granule cells of the superficial layers of the stratum granulosum formed during the 20th, 21st, and 22nd days of gestation.

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Authors and Affiliations

  1. Department of Biological Sciences, Purdue University, 47907, Lafayette, Indiana, USA

    Rodney J. Hine & Gopal D. Das

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  1. Rodney J. Hine
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  2. Gopal D. Das
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This research was supported by N.I.H. Research Grant No. NS-08817-04, and an N.I.H. Neurobiology Training Grant awarded to the senior author.

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Hine, R.J., Das, G.D. Neuroembryogenesis in the hippocampal formation of the rat. Z. Anat. Entwickl. Gesch. 144, 173–186 (1974). https://doi.org/10.1007/BF00519773

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  • DOI: https://doi.org/10.1007/BF00519773

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