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Linkage between a hemoglobin locus and albinism in the Norway rat

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Abstract

Data are reported and analyzed from intercrosses between laboratory rats heterozygous for albinism (c) and for a structural gene (designated Hbb) determining the hemoglobin polymorphism previously reported in this species. The two loci are shown to be closely linked, with a map distance of about 5 crossover units (cM). This is discussed with reference to the probable subunit structure of rat hemoglobin and to the similar linkage relationship which exists in the mouse.

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Part of a dissertation for the M.D. degree submitted to Cambridge University by E.A.F.

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French, E.A., Roberts, K.B. & Searle, A.G. Linkage between a hemoglobin locus and albinism in the Norway rat. Biochem Genet 5, 397–404 (1971). https://doi.org/10.1007/BF00485864

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