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Azaindole derivatives

LIII. New method for the synthesis of 6-chloro-5-azaindoline

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

1-Benzyl-6-hydroxy-7-cyano-5-azaindoline, which was converted to 6-chloro-5-azaindoline through 6-hydroxy-5-azaindoline, was synthesized from O-methylbutyrolactim through 1-benzyl-2-pyrrolidone, 1-benzyl-2-cyano (carbamoylmethylene)-pyrrolidine, and the product of its condensation with dimethylformamide diethylacetal.

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Literature cited

  1. A. A. Prokopov and L. N. Yakhontov, Khim. Geterotsikl. Soedin., No. 11, 1531 (1977).

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  2. V. G. Granik, N. B. Marchenko, T. F. Vlasova, and R. G. Glushkov, Khim. Geterotsikl. Soedin., No. 11, 1509 (1976).

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  3. L. N. Yakhontov and E. I. Lapan, Khim. Geterotsikl. Soedin., No. 1, 27 (1970).

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Authors and Affiliations

  1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, 119021, Moscow

    V. A. Azimov, V. G. Granik, R. G. Glushkov & L. N. Yakhontov

Authors
  1. V. A. Azimov
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  2. V. G. Granik
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  3. R. G. Glushkov
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  4. L. N. Yakhontov
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Additional information

See [1] for communication LII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 355–358, March, 1978.

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Azimov, V.A., Granik, V.G., Glushkov, R.G. et al. Azaindole derivatives. Chem Heterocycl Compd 14, 289–293 (1978). https://doi.org/10.1007/BF00470561

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  • DOI: https://doi.org/10.1007/BF00470561

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