Summary
Patients with laryngeal cancer were examined immunologically before treatment and for 1–10 years after treatment. In the pretreatment group, the percentage of T cells, lymphocyte blastoid reaction (PHA, concanavalin A), and skin reactions (PHA) were generally in the normal range, but absolute numbers of T cells and lymphocytes were reduced in most patients. In the group with no recurrence after surgery, the absolute number of T cells and lymphocytes, IgG · FcR+T cells (Tγ), and skin reactions was normal in many cases. The group with recurrence showed reduced percentage of T cells and an absolute number of T cells and lymphocytes. The absolute number of T cells and lymphocytes and the PPD skin reaction increased after surgery in some cases, but reductions in some of the parameters were noted in a few cases long after surgery. Radiation therapy for patients with tumors at early stages did not significantly change the percentage of T cells or the skin reactions.
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Read before the 5th Annual Meeting of the Japan Society of Head and Neck Tumor
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Makimoto, K., Tamada, A., Kishimoto, S. et al. Observations on immunologic parameters in laryngeal cancer patients. Arch Otorhinolaryngol 238, 241–250 (1983). https://doi.org/10.1007/BF00453935
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DOI: https://doi.org/10.1007/BF00453935