Summary
Serum testosterone levels were determined by a radioimmunological method in 102 patients with laryngeal carcinoma and in a control group of 10 healthy men. All patients were examined before the initiation of any operative or radiation therapy and after termination of treatment. The testosterone levels in the cancer patients showed a tendency toward higher values when compared with a control group of healthy men. These results indicate that hormone preparations could be considered as part of the therapy of laryngeal carcinomas.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Auletta F (1974) Methods of hormone radioimmunoassay. Jaffe BM, Behrman HR (eds) Academic Press, New York London, pp 359–370
Chan L, O'Malley BW (1976) Mechanism of action of the sex steroid hormones. N Engl J Med 294:1322–1328, 1372–1381 and 1430–1437
Dilman WM (1974) Endocrinological oncology. Medicina Moscow
Dufau ML, Catt KJ, Tsuruhara T, Ryan D (1972) Radioimmunoassay of plasma testosterone. Clin Chim Acta 37:109
Furuyama S, Mayer DM, Nugent CA (1970) A radioimmunoassay for plasma testosterone. Steroids 16:425
Pogosov WS, Kasatkin UN, Shadiev HD, Ametov LS, Smirnova LK (1977) Hormonal profile in inflammatory and cancer laryngeal processes. J Ush Gor Bol 1:16–18
Popov I, Monov N, Dimova I, Simeonov J (1976) Some peculiarities in the affection the Bulgarian population with laryngeal cancer. Bul Oncol (Sofia) 1–2: 5–7
Saez S, Saxai F (1976) Androgen receptors in human pharyngo-laryngeal mucosa and pharyngo-laryngeal epithelioma. J Steroid Biochem 7: 919–921
Sluyser M, Kassenaak AAH (1975) Mechanism of androgen action at the cellular level. Pharmacol Ther B 1: 178–188
Vermeulen A, De Sy W (1976) Androgens in patients with benign prostatic hyperplasia before and after prostatectomy. J Clin Endocrinol Metabol 43: 1250–1254
Wickings EJ, Nieschlag E (1976) Stability of testosterone and androstenedione in blood and plasma samples. Clin Chim Acta 7: 439–443
Wynder EL, Covey LS, Malbuchi K, Mushinski M (1976) Environmental factors in cancer of the larynx. Cancer 38: 1591–1601
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Haidoutova, R., Melamed, M., Dimitrova, S. et al. Investigations of serum testosterone levels in patients with laryngeal cancers. Arch Otorhinolaryngol 241, 213–217 (1985). https://doi.org/10.1007/BF00453690
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00453690