Abstract
The results of a study comparing the ability of 99Tcm-sulphur colloid and 99Tcm-HIDA to demonstrate circumscribed defects and obstruction of the biliary flow to the intestines are reported. As regards focal liver diseases, colloid scintigraphy (SC) had a nosographic sensitivity and specificity of 0.87 and 0.85, respectively. The corresponding figures for the HIDA scintigraphy were 0.40 and 0.92. The sensitivities are significantly different. Concerning the diagnosis of extrahepatic obstruction, sulphur colloid scintigraphy had a nosographic sensitivity and specificity of 0.31 and 0.94. The corresponding figures for HIDA scintigraphy were 0.69 and 0.84. These sensitivities are significantly different too. The most frequent cause of false results was a pattern of hepatocellular disease in sulphur colloid scans in patients with a longstanding biliary obstruction. The second most frequent error was due to circumscribed defects in SC as well as in HIDA scans in patients with obstructive diseases and a high value of serum bilirubin. A third source of error was the pattern of an obstruction in HIDA scans in patients with focal diseases. The significance of the star pattern the sulphur colloid scan in patients with obstruction is stressed, as the significance of this pattern not has been evaluated previously. It is concluded that the two different scintigraphic methods are complementary tools in the examination of patients with liver diseases
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Pedersen, S.A., Øster-Jørgensen, E. & Schoubye, J. Hepatobiliary scintigraphy with 99Tcm-HIDA and 99Tcm-sulphur colloid. Eur J Nucl Med 5, 305–309 (1980). https://doi.org/10.1007/BF00445615
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DOI: https://doi.org/10.1007/BF00445615