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Modifications of serum glycoproteins the days following a prolonged physical exercise and the influence of physical training

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Summary

Eight male subjects (mean age 24.1±2.6 years) performed at intervals of 2 weeks successively a 3 h and two 2 h runs of different running speed. The days following the running there were moderate elevations of C-reactive protein, haptoglobin, alpha-1-acid glycoprotein, coeruloplasmin, transferrin, alpha-1-antitrypsin and plasminogen. There were small or no changes of albumin, alpha-2-macroglobulin and hemopexin. The elevations of the “acute phase reactants” were examined in three male subjects following a 2 h run before and after an endurance training period of 9 weeks. This demonstrated a decreased acute phase response after training as illustrated by the changes of C-reactive protein, haptoglobin and alpha-1-acid glycoprotein in spite of higher posttraining running speeds. Well-trained athletes have elevated levels of the serum protease inhibitors alpha-1-antitrypsin, alpha-2-macroglobulin and C1-inhibitor. These antiproteolytic glycoproteins might limit exercise-induced inflammatory reactions.

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  1. Institute for Sports-Medicine and Cardiology, German Sport-University, DSHS, Carl-Diem-Weg, D-5000, Köln 41, Federal Republic of Germany

    H. Liesen, B. Dufaux & W. Hollmann

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  1. H. Liesen
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  2. B. Dufaux
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  3. W. Hollmann
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This research was supported by the “Bundesinstitut für Sportwissenschaften (Köln-Lövenich)”

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Liesen, H., Dufaux, B. & Hollmann, W. Modifications of serum glycoproteins the days following a prolonged physical exercise and the influence of physical training. Europ. J. Appl. Physiol. 37, 243–254 (1977). https://doi.org/10.1007/BF00430954

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