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Behavioural and electrocortical modifications induced in the rat by intraventricular injection of physalaemin and eledoisin

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Abstract

The effects of intraventricular injection of eledoisin and physalaemin in the rat were studied. Both peptides reduced explorative behaviour; eledoisin, but not physalaemin, produced catatonia, reduction of muscular strength, tremor and sialorrhea. The electrocorticogram showed the signs of a depressive effect both after physalaemin and eledoisin administration.

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Authors and Affiliations

  1. Institute of Pharmacology and Pharmacognosy, Faculty of Pharmacy, University of Camerino, Italy

    G. de Caro, L. G. Micossi & F. Venturi

  2. Institute of Physiology, Faculty of Medicine, University of L'Aquila, Italy

    A. Brancati & E. Scarnati

Authors
  1. G. de Caro
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  2. L. G. Micossi
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  3. F. Venturi
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  4. A. Brancati
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  5. E. Scarnati
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de Caro, G., Micossi, L.G., Venturi, F. et al. Behavioural and electrocortical modifications induced in the rat by intraventricular injection of physalaemin and eledoisin. Psychopharmacologia 38, 211–218 (1974). https://doi.org/10.1007/BF00421373

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  • DOI: https://doi.org/10.1007/BF00421373

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