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Stably DNA-bound chromosomal proteins

  • Chromosoma Focus
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Abstract

DNA accomplishes its biological function in a complex with nuclear proteins. A minor protein fraction has been found in chromatin which could not be dissociated from DNA by reagents abolishing non-covalent type of interactions. The controversy surrounding the nature of the protein moiety and the nature of the bond linking the two components on the one hand, and the fact pointing to its evolutionary conservatism and metabolic stability on the other, make it necessary to critically evaluate the data in view of the possible biological function for such proteins.

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  1. Zoya Avramova

    Present address: Department of Biological Sciences, Purdue University, 47907, W. Lafayette, IN, USA

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  1. Institute of Molecular Biology, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria

    Roumen Tsanev & Zoya Avramova

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  1. Roumen Tsanev
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  2. Zoya Avramova
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Tsanev, R., Avramova, Z. Stably DNA-bound chromosomal proteins. Chromosoma 103, 293–301 (1994). https://doi.org/10.1007/BF00417876

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