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A comparison of 2,3-dihydro-lysergic acid diethylamide with LSD-25

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Summary

  1. 1.

    The 2,3-dihydro-diethylamide of lysergic acid induces LSD-like autonomic and mental changes in man but is less potent than LSD.

  2. 2.

    The effects of 2,3-DH-LSD appear more slowly than those of LSD-25.

  3. 3.

    The low potency (relative to LSD-25) of 2,3-DH-LSD in inducing fever in rabbits correlates with a relatively low potency in inducing autonomic and psychotomimetic effects in man.

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References

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Authors and Affiliations

  1. U.S. Department of Health, Education and Welfare, Public Health Service, National Institute of Mental Health, Addiction Research Center, PHS Hospital, Lexington, Kentucky, USA

    Charles W. Gorodetzky & Harris Isbell

  2. Department of Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA

    Charles W. Gorodetzky & Harris Isbell

Authors
  1. Charles W. Gorodetzky
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  2. Harris Isbell
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Gorodetzky, C.W., Isbell, H. A comparison of 2,3-dihydro-lysergic acid diethylamide with LSD-25. Psychopharmacologia 6, 229–233 (1964). https://doi.org/10.1007/BF00404013

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  • DOI: https://doi.org/10.1007/BF00404013

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