Skip to main content
SpringerLink
Log in

Nicotine injections as the conditioned stimulus in discrimination learning

  • Original Investigations
  • Published:
Psychopharmacologia Aims and scope Submit manuscript

Summary

Rats were trained to respond for water rewards on different bars in a Skinner box depending on whether they had previously been injected with nicotine or with saline. No other drug tested could consistently elicit responses on the “nicotine correct” bar. Pre-treatment with mecamylamine abolished the rats' ability to distinguish between nicotine and saline but pretreatment with chlorisondamine did not.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Conger, J. J.: The effects of alcohol on conflict behavior in the albino rat. Quart. J. Stud. Alcohol 12, 1–29 (1951).

    Google Scholar 

  • Cook, L., A. Davidson, D. J. Davis, and R. T. Kelleher: Epinephrine, norepinephrine and acetylcholine as conditioned stimuli for avoidance behavior. Science 131, 990–991 (1960).

    Google Scholar 

  • Morrison, C. F.: Effects of nicotine on operant behaviour of rats. Int. J. Neuropharmacol. 6, 229–240 (1967).

    Google Scholar 

  • —: The modification by physostigmine of some effects of nicotine on bar-pressing behaviour of rats. Brit. J. Pharmacol. 32, 28–33 (1968).

    Google Scholar 

  • —: The effects of nicotine on punished behaviour. Psychopharmacologia (Berl.) 14, 221–232 (1969).

    Google Scholar 

  • —, and A. K. Armitage: Effects of nicotine upon the free operant behavior of rats and spontaneous motor activity of mice. Ann. N. Y. Acad. Sci. 142, 268–276 (1967).

    Google Scholar 

  • —, J. M. Goodyear, and C. M. Sellers: Antagonism by antimuscarinic and ganglionblocking drugs of some of the behavioural effects of nicotine. Psychopharmacologia (Berl.) 15, 341–350 (1969).

    Google Scholar 

  • —, and P. N. Lee: A comparison of the effects of nicotine and physostigmine on a measure of activity in the rat. Psychopharmacologia (Berl.) 13, 210–221 (1968).

    Google Scholar 

  • Oliverio, A.: Effects of scopolamine on avoidance conditioning and habituation of mice. Psychopharmacologia (Berl.) 12, 214–226 (1968).

    Google Scholar 

  • Overton, D. A.: State dependent or dissociated learning produced with pentobarbital. J. comp. physiol. Psychol. 57, 3–12 (1964).

    Google Scholar 

  • Stewart, J.: Differential responses based on the physiological consequences of pharmacological agents. Psychopharmacologia (Berl.) 3, 132–138 (1962).

    Google Scholar 

  • Wanner, H. U., and K. Bättig: Wirkung von Nikotin und Amphetamin auf die Selbstreizung bei der Ratte. Helv. physiol. pharmacol. Acta 24, 122–124 (1966).

    Google Scholar 

  • — —: Die Wirkung von Nikotin und Apmhetamin auf die subcortikale Selbstreizung der Ratte. Z. Präv.-Med. 13, 101–110 (1968).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Tobacco Research Council Laboratories, Harrogate, England

    Cathleen F. Morrison & Jane A. Stephenson

Authors
  1. Cathleen F. Morrison
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jane A. Stephenson
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Morrison, C.F., Stephenson, J.A. Nicotine injections as the conditioned stimulus in discrimination learning. Psychopharmacologia 15, 351–360 (1969). https://doi.org/10.1007/BF00403710

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00403710

Key-Words

Search

Navigation