Abstract
A monoclonal antibody known to recognize the H-2.m3 specificity is shown to react with the class I H-2 product of t Lub-1 but not t w12 tf mice. This reagent was used to study the segregation of the H-2 complex in the progeny of t Lub-1 +/t ww12 tf females. The most straightforward interpretation of the results presented here is that these t haplotypes carry an H-2 complex located between the centromere and tufted locus. Possible consequences of such a location with regard to the recombination between t haplotypes and chromosome 17 from laboratory mice are discussed.
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Plat, M., Condamine, H. Recombination between two mouse t haplotypes (t w12 tf) and t Lub-1) : Mapping. of the H-2 complex relative to centromere and tufted (tf) locus. Immunogenetics 20, 277–285 (1984). https://doi.org/10.1007/BF00364209
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DOI: https://doi.org/10.1007/BF00364209