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The Anatomy and Physiology of Laboratory Mouse

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Essentials of Laboratory Animal Science: Principles and Practices

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Abstract

Among the different types of vertebrate and invertebrate animals used in biomedical research, the laboratory mouse is the widely used vertebrate animal model. It remains the choice of model for many research hypotheses due to its small size, shorter life span, easy maintenance, short generation time and manipulable genetics. The mouse is used in understanding basic research, testing, teaching, genetics, physiology, psychology and many more areas of biomedical research. An important advancement in this regard is the whole-genome sequencing of both human and mouse; and both share synteny of chromosomes. This chapter reviews the existing and new unique features of the anatomy and physiology of mouse and their suitability to different experimental designs.

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Abbreviations

AQCS:

Animal Quarantine and Certification Services

FSH:

Follicle-stimulating hormone

GG:

Grueneberg ganglion

HVAC:

Heating, ventilation, and air conditioning

ICC:

Interstitial cells of Cajal

LA:

Left auricle

LH:

Luteinising hormone

LV:

Left ventricle

MOE:

Main olfactory epithelium

MUP:

Mouse urinary protein

NALT:

Nasal-associated lymphoid tissue

pRGCs:

Photosensitive retinal ganglion cells

RA:

Right auricle

RV:

Right ventricle

SG:

Salivary gland

SOO:

Septal olfactory organ

VNO:

Vomeronasal organ

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Authors and Affiliations

  1. Institute of Life Sciences, Bhubaneswar, India

    Sarita Jena

  2. National Institute of Science Education and Research, Bhubaneswar, India

    Saurabh Chawla

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  1. Sarita Jena
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  2. Saurabh Chawla
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Corresponding author

Correspondence to Sarita Jena .

Editor information

Editors and Affiliations

  1. Experimental Animal Facility, National Institute of Immunology, New Delhi, Delhi, India

    P. Nagarajan

  2. Central Animal Facility, Indian Institute of Science, Bangalore, Karnataka, India

    Ramachandra Gudde

  3. Veterinary Pharmacology and Toxicology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India

    Ramesh Srinivasan

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Jena, S., Chawla, S. (2021). The Anatomy and Physiology of Laboratory Mouse. In: Nagarajan, P., Gudde, R., Srinivasan, R. (eds) Essentials of Laboratory Animal Science: Principles and Practices. Springer, Singapore. https://doi.org/10.1007/978-981-16-0987-9_8

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