Abstract
The biocompatibility of two types of radiopaque tantalum markers was evaluated histologically. Reactions to pin markers (99.9% purity) and spherical markers (95.2% purity) were investigated after 3–6 weeks in rabbits and 5–48 weeks in children with abnormal growth. Both marker types were firmly attached to bone trabeculae; this was most pronounced in rabbit bone, and no adverse macroscopic reactions were observed. Microscopically, no reactions or only slight fibrosis of bone tissue were detected, while soft tissues only demonstrated a minor inflammatory reaction. Nevertheless, the need for careful preparation and execution of marker implantations is stressed, and particularly avoidance of the use of emery in sharpening of cannulae. The bioinertness of tantalum was reconfirmed as was its suitability for use as skeletal and soft tissue radiographic markers.
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References
Alberius P (1983) Bone reactions to tantalum markers. A scanning electron microscopic study. Acta Anat (Basel) 115:310
Aronson AS (1976) X-ray stereophotogrammetry of longitudinal bone growth. Thesis, University of Lund, Lund, Sweden
Aronson AS, Holst L, Selvik G (1974) An instrument for insertion of radiopaque bone markers. Radiology 113:733
Björk A (1963) Variations in the growth pattern of the human mandible: Longitudinal radiographic study by the implant method. J Dent Res 42:400
Björk A (1968) The use of metallic implants in the study of facial growth in children. Method and application. Am J Phys Anthropol 29:243
Björk A, Skieller V (1983) Normal and abnormal growth of the mandible. A synthesis of longitudinal cephalometric implant studies over a period of 25 years. Eur J Orthod 5:1
Burke GL (1940) The corrosion of metals in tissues; and an introduction to tantalum. Can Med Assoc J 43:125
Claesson G, Fredlund P, Mühlow A, Selvik G (1978) Roentgen stereophotogrammetry for evaluation of liver volume and shape. Acta Radiol [Diagn] (Stockh) 19:423
Grundschober F, Kellner G, Eschberger J, Plenk H Jr (1980) Long-term osseous anchorage of endosseous dental implants made of tantalum and titanium. 1st. Wld Biomaterials Congress, Baden, p 365
Masmonteil MF (1935) De quelques cas d'ostéite électrolytique. Bull Soc Chir (Paris) 27:338
McFadden JT (1969) Metallurgical principles in neurosurgery. J Neurosurg 31:373
Nadel JA, Wolfe WG, Graf PD (1968) Powdered tantalum as a medium for bronchography in canine and human lungs. Invest Radiol 3:229
Pflüger G, Plenk H Jr, Böhler N, Grundschober F, Schider S (1980) Bone reactions to porous and grooved stainless steel, tantalum and niobium implants. 1st. Wld Biomaterials Congress, Baden, p 45
Samuels PB, Roedling H, Katz R, Cincotti JJ (1966) A new hemostatic clip: 2-year review of 1007 cases. Ann Surg 163:427
Sarnat BG, Selman AJ (1978) Growth pattern of the rabbit nasal bone region. A combined serial gross and radiographic study with metallic implants. Acta Anat (Basel) 101:193
Schider S, Bildstein H (1980) Tantalum and niobium as potential prosthetic materials. 1st. Wld Biomaterials Congress, Baden, p 13
Selvik G (1974) A roentgen stereophotogrammetric method for the study of the kinematics of the skeletal system. Thesis, University of Lund, Lund, Sweden
Tropé C, Selvik G, Kullander S, Mattsson W, Mühlow A, Åstedt B (1978) Antineoplastic drug effect evaluated with a new X-ray stereophotographic measurement of the tumor volume. Curr Chemother 1137
von Holst H, Collins P, Steiner L (1981) Titanium, silver, and tantalum clips in brain tissue. Acta Neurochir (Wien) 56:239
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Aronson, A.S., Jonsson, N. & Alberius, P. Tantalum markers in radiography. Skeletal Radiol 14, 207–211 (1985). https://doi.org/10.1007/BF00355566
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DOI: https://doi.org/10.1007/BF00355566