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Morphologische Variabilität der chromosomalen Funktionsstrukturen in den Spermatocytenkernen von Drosophila-Arten

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Abstract

In the genus Drosophila the nuclei of primary spermatocytes contain special chromosomal functional structures which are organized as the pairs of lateral loops in lampbrush chromosomes. In each species the loops have their own species specific morphology. The morphological variability of the spermatocyte structures in 54 Drosophila species is described. Although the nuclei of spermatids are synthetically inactive, the cells are able to synthesize proteins which are essential for the differentiation of sperm. Therefore, special mechanisms are necessary for the preformation, stabilization, and programmed packaging of gene products during the spermatocyte stage. This may be the function of the spermatocyte loops.

Zusammenfassung

In der Gattung Drosophila treten in den Zellkernen von primären Spermatocyten chromosomale Funktionsstrukturen auf, die im Prinzip wie die lateralen Schleifenpaare von Lampenbürstenchromosomen organisiert sind. Die Form der Schleifen ist bei jeder Art in artspezifischer Weise abgewandelt. Die morphologische Variabilität der Spermatocytenstrukturen von 54 Drosophila-Arten wird beschrieben. Das genetische Material in den Schleifen spielt möglicherweise eine entscheidende Rolle bei der Vorfertigung, Stabilisierung und programmierten Verpackung von Genprodukten, die erst in späteren Stadien während der Spermiohistogenese in den Zellen verbraucht werden.

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Literatur

  • Beermann, W.: Operative Gliederung der Chromosomen. Naturwissenschaften 52, 365–375 (1965); - Differentiation at the level of the chromosomes. In: Cell differentiation and morphogenesis, p. 24–54. Amsterdam: North-Holland Publ. Co. 1966.

    Google Scholar 

  • Berlowitz, L.: Correlation of genetic activity, heterochromatization, and RNA metabolism. Proc. nat. Acad. Sci. (Wash.) 53, 68–73 (1965).

    Google Scholar 

  • Brown, D. D., and E. Littna: RNA synthesis during the development of Xenopus laevis, the South African clawed toad. J. molec. Biol. 8, 669–687 (1964a); - Variations in the synthesis of stable RNA's during oogenesis and development of Xenopus laevis. J. molec. Biol. 8, 688–695 (1964b); - Synthesis and accumulation of DNA-like RNA during embryogenesis of Xenopus laevis. J. molec. Biol. 20, 81–94 (1966a); - Synthesis and accumulation of low molecular weight RNA during embryogenesis of Xenopus laevis. J. molec. Biol. 20, 95–121 (1966b).

    Google Scholar 

  • Callan, H. G.: The lampbrush chromosomes of Sepia officinalis, Anilocra physodes, and Scyllium catulus, and their structural relationship to the lampbrush chromosomes of Amphibia. Pubbl. Staz. Zool. Napoli 29, 329–346 (1957); - The nature of lampbrush chromosomes. Int. Rev. Cytol. 15, 1–34 (1963).

    Google Scholar 

  • Davidson, E. H., V. G. Allfrey, and A. E. Mirsky: On the RNA synthesized during the lampbrush phase of amphibian oocytes. Proc. nat. Acad. Sci. (Wash.) 52, 501–508 (1964).

    Google Scholar 

  • —, M. Crippa, F. R. Kramer, and A. E. Mirsky: Genomic function during the lampbrush chromosome stage of amphibian oogenesis. Proc. nat. Acad. Sci. (Wash.) 56, 856–863 (1966).

    Google Scholar 

  • —, G. W. Haslett, R. J. Finney, V. G. Allfrey, and A. E. Mirsky: Evidence for the prelocalization of cytoplasmic factors affecting gene activation in early embryogenesis. Proc. nat. Acad. Sci. (Wash.) 54, 696–704 (1965).

    Google Scholar 

  • Gall, J. G., and H. G. Callan: H3 uridine incorporation in lampbrush chromosomes. Proc. nat. Acad. Sci. (Wash.) 48, 562–570 (1962).

    Google Scholar 

  • Gross, P. R., and G. H. Cousineau: Macromolecule synthesis and the influence of actinomycin on early development. Exp. Cell Res. 33, 368–395 (1964).

    Google Scholar 

  • —, L. I. Malkin, and M. Hubbard: Synthesis of RNA during oogenesis in the seaurchin. J. molec. Biol. 13, 463–481 (1965).

    Google Scholar 

  • Gross, P. R., L. I. Malkin, and W. A. Moyer: Templates for the first proteins of embryonic development. Proc. nat. Acad. Sci. (Wash.) 51, 407–414 (1964).

    Google Scholar 

  • Gurdon, J. B., and D. D. Brown: Cytoplasmic regulation of RNA synthesis and nucleolus formation in developing embryos of Xenopus laevia. J. moleo. Biol. 12, 27–35 (1965).

    Google Scholar 

  • Henderson, S. A.: The chromosomes of the British Tetrigidae. Chromosoma (Berl.) 12, 553–572 (1961); - RNA synthesis during male meiosis and spermiogenesis. Chromosoma (Berl.) 15, 345–366 (1964).

    Google Scholar 

  • Hess, O.: Strukturdifferenzierungen im Y-Chromosom von Drosophila hydei und ihre Beziehungen zu Gen-Aktivitäten. I. Mutanten der Funktionsstrukturen. Zool. Anz., Suppl. 28, 156–163 (1965a); - III. Sequenz und Lokalisation der Schleifenbildungsorte. Chromosoma (Berl.) 16, 222–248 (1965b); - Structural modifications of the Y chromosome in Drosophila hydei and their relations to gene activity. In: C. D. Darlington and K. R. Lewis (eds.), Chromosomes today vol. 1, p. 167–173. London: Oliver & Boyd 1966(a); - Funktionelle und strukturelle Organisation der Lampenbürstenchromosomen. In: P. Sitte (Hrsg.), Probleme der biologischen Reduplikation, S. 29–54. Berlin-Heidelberg-New York: Springer 1966(b); - Genetic control of differentiation in male germ line cells of Drosophila. Exp. biol. Med. 1 (1967) (im Druck).

    Google Scholar 

  • —, and G. F. Meyer: Chromosomal differentiations of the lampbrush type formed by the Y chromosome in Drosophila hydei. J. Cell Biol. 16, 527–539 (1963a); - Artspezifische funktionelle Differenzierungen des Y-Heterochromatins bei Drosophila-Arten der D. hydei-Subgruppe. Portug. Acta biol. (A) 7, 29–46 (1963b) (Festschr. für E. Heitz); - Genetic activities of the Y chromosome in Drosophila during spermatogenesis. Advanc. Genet. 14 (im Druck).

    Google Scholar 

  • Izawa, M., V. G. Allfrey, and A. E. Mirsky: The relationship between RNA synthesis and loop structure in lampbrush chromosomes. Proc. nat. Acad. Sci. (Wash.) 49, 544–551 (1963a); - Composition of the nucleus and chromosomes in the lampbrush stage of the newt oocyte. Proc. nat. Acad. Sci. (Wash.) 50, 811–817 (1963b).

    Google Scholar 

  • Kunz, W.: Zur Chromosomenstruktur in den Oocyten der Heuschrecke Locusta migratoria. Naturwissenschaften 53, 23 (1966); - Funktionsstrukturen im Oocytenkern von Locusta migratoria. Chromosoma (Berl.) 20, 332–370 (1967); - Lampenbürstenchromosomen und multiple Nukleolen bei Orthopteren. Chromosoma (Berl.) (im Druck).

    Google Scholar 

  • Lewis, K. R., and G. C. Scudder: The chromosomes of Dicranocephalus agilis. Cytologia (Tokyo) 23, 92–104 (1958).

    Google Scholar 

  • Meyer, G. F.: Die Funktionsstrukturen des Y-Chromosoms in den Spermatocytenkernen von Drosophila hydei, D. neohydei, D. repleta und einigen anderen Drosophila-Arten. Chromosoma (Berl.) 14, 207–255 (1963).

    Google Scholar 

  • —, u. O. Hess: Struktur-Differenzierungen im Y-Chromosom von Drosophila hydei und ihre Beziehungen zu Gen-Aktivitäten. II. Effekt der RNS-Synthese-Hemmung durch Actinomycin. Chromosoma (Berl.) 16, 249–270 (1965).

    Google Scholar 

  • —, u. W. Beermann: Phasenspezifische Funktionsstrukturen in den Spermatocytenkernen von Drosophila melanogaster und ihre Abhängigkeit vom Y-Chromosom. Chromosoma (Berl.) 12, 676–716 (1961).

    Google Scholar 

  • Monesi, V.: Ribonucleic acid synthesis during mitosis and meiosis in the mouse testis. J. Cell Biol. 22, 521–532 (1964); - Synthetic activities during spermatogenesis in the mouse. Exp. Cell Res. 39, 197–224 (1965).

    Google Scholar 

  • Nebel, B. R., and E. M. Coulon: The fine structure of chromosomes in pigeon spermatocytes. Chromosoma (Berl.) 13, 272–291 (1962).

    Google Scholar 

  • Olivieri, G., and A. Olivieri: Autoradiographic study of nucleic acid synthesis during spermatogenesis in Drosophila melanogaster. Mutat. Res. 2, 366–380 (1965).

    Google Scholar 

  • Patterson, J. T., and W. S. Stone: Evolution in the genus Drosophila. New York: MacMillan & Co. 1952.

    Google Scholar 

  • Ris, H.: The structure of meiotic chromosomes in the grasshopper and its bearing on the nature of „chromomeres“ and „lampbrush chromosomes“. Biol. Bull. 89, 242–257 (1945); - Chromosome structure. In: W.M. McElroy (ed.), The chemical basis of heredity, p. 23–62. Baltimore: Johns Hopkins Univ. Press 1957.

    Google Scholar 

  • Telfer, W. H.: The mechanism and control of yolk formation. Ann. Rev. Entomol. 10, 161–184 (1965).

    Google Scholar 

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Authors and Affiliations

  1. Max-Planck-Institut für Biologie, Abteilung Beermann, Tübingen

    Oswald Hess

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  1. Oswald Hess
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Herrn Prof. Dr. W. E. Ankel, meinem verehrten Lehrer, zum 70. Geburtstag gewidmet.

Verfasser dankt der Deutschen Forschungsgemeinschaft für eine Reisebeihilfe. Die Untersuchungen werden jetzt ebenfalls mit Unterstützung durch die Deutsche Forschungsgemeinschaft fortgesetzt. Mein besonderer Dank gilt Herrn Prof. Dr. W. S. Stone und seinen Mitarbeitern von der Genetics Foundation an der Universität von Texas in Austin. Die Zeichnungen wurden von Herrn E. Freiberg angefertigt.

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Hess, O. Morphologische Variabilität der chromosomalen Funktionsstrukturen in den Spermatocytenkernen von Drosophila-Arten. Chromosoma 21, 429–445 (1967). https://doi.org/10.1007/BF00336951

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