Summary
Plasmids R124 and R124/3 carry genes coding for two different R-M systems and normally only one set of genes is expressed. These genes can be translocated to F plasmids that are compatible with the R factors and in strains carrying these F plasmids and an R factor a trans-acting regulatory mechanism switches off the expression of R-M genes on the introduced plasmid. Additionally the unexpressed genes on the introduced plasmid are expressed. The regulatory mechanism controlling the alternative expression of R124 and R124/3 R-M genes involves a physical rearrangement of DNA sequences.
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Communicated by J. Schell
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Glover, S.W., Firman, K., Watson, G. et al. The alternate expression of two restriction and modification systems. Mol Gen Genet 190, 65–69 (1983). https://doi.org/10.1007/BF00330325
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DOI: https://doi.org/10.1007/BF00330325