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High molecular weight copolymers of l-lactide and ε-caprolactone as biodegradable elastomeric implant materials

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Summary

High molecular weight copolymers of L-lactide and ε-caprolactone have been synthesized by ring opening copolymerization with stannous octoate as catalyst. The good mechanical properties of the 50/50 copolymers make it a suitable material for biomedical applications such as nerve guides etc., where degradation of the elastomeric implant is required. In contrast to the frequently used MDI containing polyurethanes, degradation products of the P(LLA-ε-CL) are non toxic. The use of such a material is therefore preferable.

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Authors and Affiliations

  1. Laboratory of Polymer Chemistry, University of Groningen, Nijenborgh 16, NL-9747 AG, Groningen, The Netherlands

    D. W. Grijpma, G. J. Zondervan & A. J. Pennings

Authors
  1. D. W. Grijpma
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  2. G. J. Zondervan
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  3. A. J. Pennings
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Grijpma, D.W., Zondervan, G.J. & Pennings, A.J. High molecular weight copolymers of l-lactide and ε-caprolactone as biodegradable elastomeric implant materials. Polymer Bulletin 25, 327–333 (1991). https://doi.org/10.1007/BF00316902

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  • DOI: https://doi.org/10.1007/BF00316902

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