Summary
Central pontine myelinolysis (CPM) developed in association with acute adrenocortical insufficiency during correction of severe hyponatraemia in a 58-year-old woman. Repeated CT scanning and NMR imaging were normal from the onset of the illness. Electroencephalography and brainstem auditory evoked responses showed abnormalities consistent with a brain-stem lesion, which resolved as the patient made a gradual but incomplete recovery. Our observations illustrate the value of electrophysiological monitoring in CPM and support the proposed association between this condition and the rapid correction of an electrolyte imbalance.
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Ingram, D.A., Traub, M., Kopelman, P.G. et al. Brain-stem auditory evoked responses in diagnosis of central pontine myelinolysis. J Neurol 233, 23–24 (1986). https://doi.org/10.1007/BF00313986
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DOI: https://doi.org/10.1007/BF00313986