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Composite cerebral metastasis and oligodendroglioma: an exceptional form of mixed neoplasia

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Abstract

Our report describes the uncommon case of a 61 year old female patient who underwent a left parietooccipital craniotomy and extirpation of a malignant tumor. Histological examination revealed a metastatic carcinoma of mammary origin intimately intermingled with a calcified oligodendroglioma WHO II. The preexisting oligodendroglial part had been detected four years before, but since then had been misinterpreted as a glious scar resulting from a previous brain trauma. Three years before neurosurgical intervention, the patient had undergone a left side mastectomy. The histological finding at that time was a solid breast tumour WHO T1N0. The occurence of cerebral mixed neoplasias and possible causal factors are discussed.

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References

  1. Bonnin JM, CE Pena, LJ Rubinstein: Mixed capillary hemangioblastoma and glioma. A redefinition of the “angioblastoma”. J. Neuropathol Exp Neurol 42 (1983) 504–616

    Google Scholar 

  2. Jamjoom A, N Kane, J Nicoll: Metastasis of a renal carcinoma to a cerebellar haemangioblastoma in a case of von Hippel-Lindau disease. Neurosurg Rev 15 (1992) 231–234

    Google Scholar 

  3. Jänisch W, D Schreiber, H Güthert: Neuropathologie—Tumoren des Nervensystems VEB Gustav Fischer Verlag, Jena 1988

    Google Scholar 

  4. Kano M, S Hashimoto, T Kondo, K Yamada, K Koshino: Mixed glioma and teratoid tumor coexisting in the right cerebral hemisphere of a 2-year-old girl. Child's Brain 8 (1981) 318

    Google Scholar 

  5. Le Blanc RA: Metastasis of bronchogenic carcinoma to acoustic neurinoma. J Neurosurg 41 (1974) 614

    Google Scholar 

  6. Lukes SA, R Wollmann, K Stefannson: Meningeal sarcomatosis and multiple astrocytomas. Arch Neurol 40 (1983) 179–182

    Google Scholar 

  7. Manuelidis EE, GB Solitare: Pathology of the nervous system. McGraw-Hill, New York 1971

    Google Scholar 

  8. Molnar P, K Hegedüs: Adjacent astrocytoma and ependymoma: dependent mixed neoplasia or unusual collision tumor?. Surg Neurol 22 (1984) 455–460

    Google Scholar 

  9. Mörk SJ, LJ Rubinstein: Metastatic carcinoma to glioma. A report of three cases with a critical review of the literature. J Neurol, Neurosurg and Psychiatry 51 (1988) 256

    Google Scholar 

  10. Ng HK, STH Lo: Cytokeratin immunoreactivity in gliomas. Histopathology 14 (1989) 359–368

    Google Scholar 

  11. Russel D, L Rubinstein: Pathology of the Nervous System. 5th ed. Edward Arnold, London 1989

    Google Scholar 

  12. Steinberg GK, LM Rowan, WJ White, DA Kristt: An unusual neoplasm of the cauda equina with gangliomatous and ependymatous elements. Surg Neurol 22 (1984) 164–166

    Google Scholar 

  13. Strang RR: Metastasis of breast carcinoma to an intracerebral oligodendroglioma. Zentralblatt für Neurochirurgie 25 (1965) 206

    Google Scholar 

  14. Tang TT, JM Harb, SJ Mork, JR Sty: Composite cerebral neuroblastoma and astrocytoma. A mixed central neuroepithelial tumour. Cancer 56 (1985) 1404–1412

    Google Scholar 

Download references

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Wurm, G., Huber, A., Hiertz, H. et al. Composite cerebral metastasis and oligodendroglioma: an exceptional form of mixed neoplasia. Neurosurg. Rev. 17, 291–294 (1994). https://doi.org/10.1007/BF00306820

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  • DOI: https://doi.org/10.1007/BF00306820

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