Effect of excess glucose on the carbohydrates, water and fat contents of the tissues of Clarius lazera

Summary

• 1. The extent of deposition of glycogen and fat as well as the degree of dilution of different tissues of Clarius lazera after the administration of different doses of glucose solution was worked out.

• 2. After low doses of glucose 2 gm/kilo gm body weight, the rise in carbohydrate content of all the tissues is noted ecxept the skin, and heart.

• 3. In all cases studied the higher the dose given to the experimental animal, the more marked is the increase in glycogen content of tissues.

• 4. The respiratory organ and brain are the only tissues which after a certain stage of storage of carbohydrates, can retain no more glycogen, even if the dose glucose is increased.

• 5. Maximum deposition of glycogen occurs in liver and skeletal muscles. Then follows the plain muscles of stomach and spleen. The rise of glycogen in the remaining tissues as the heart, kidney, ovary and skin is less pronounced.

• 6. All the tissues of the body except blood, skin and ovary keep their water content more or less constant. Thus no load of water was permitted to remain within the tissues of the fish.

• 7. No rise in the fat content of the tissues of Clarius occurs after feeding even with high doses of glucose solution 10 gm/kilo gm body weight, which may indicate that process of interconversion of glucose into fat does not take place at these doses.