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Inversion of ‘fluorescent’ segment in chromosome 3: A polymorphic trait

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Summary

The frequency of the ‘inversion’ of fluorescent constitutive heterochromatin in chromosome 3 was the same in a sample of 370 retarded persons as in a sample of 222 mentally normal men. It can be concluded that this ‘inversion’ is not associated with mental retardation. This variant is more common (4%) in the Canadian population we studied than in samples reported by most other authors (0–1.7%). Possibly the founder effect could play a role in the differences. Two cases of homozygotes for this ‘inversion’ were identified.

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Authors and Affiliations

  1. Cytogenetics Laboratory, Queen's University K.P.H. Kingston, K7L 4X3, Ontario, Canada

    D. Soudek & Helena Sroka

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  1. D. Soudek
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  2. Helena Sroka
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Soudek, D., Sroka, H. Inversion of ‘fluorescent’ segment in chromosome 3: A polymorphic trait. Hum Genet 44, 109–115 (1978). https://doi.org/10.1007/BF00295403

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