Summary
A correlation between Y chromosome length and stature was statistically analyzed in a normal male population of 142 Japanese students with a mean age of 24.0 years. Evidence was obtained that increased length of the heterochromatic band Yq12 may be associated with increased height: The correlation coefficient between band Yq12 length and height was 0.17, statistically significant at the 5% level. And, taller males had longer Y chromosomes, in which the mean length of band Yq12 was significantly longer than that of shorter males. No correlation was seen between length of the euchromatic band Yq11 and stature. The present study reveals a possible effect of Yq heterochromatin on the development of body height in man.
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Baekgaard W, Nielsen J (1975) Y chromosome length, extroversion-introversion and neuroticism. Br J Soc Clin Psychol 14:197–198
Benezech M, Noël B, Travers E, Mottet J (1976) Conduite antisociale et longueur du chromosome Y. Hum Genet 32:77–80
Bobrow M, Pearson PL, Pike MC, Al-Alfi OS (1971) Length variation in the quinacrine binding segment of human Y chromosome of different sizes. Cytogenetics 10:190–198
Brøgger A, Urdal T, Larsen FB, Lavik NJ (1977) No evidence for a correlation between behaviour and the size of the Y chromosome. Clin Genet 11:349–358
Christensen KR, Nielsen J (1974) Incidence of chromosome aberrations in a child psychiatric hospital. Clin Genet 5:205–210
Cohen MM, Shaw MW, MacCluer JW (1966) Racial differences in the length of the human Y chromosome. Cytogenetics 5:34–52
Court Brown WM (1967) In: Human population cytogenetics. North-Holland Publ Co, Amsterdam
El-Alfi CM (1970) A family with a large Y chromosome. J Med Genet 7: 37–40
Furusho T (1974a) An estimate of the number of gene loci responsible for stature in the growth period. Jpn J Hum Genet 18:311–355
Furusho T (1974b) Genetic study on stature. Jpn J Hum Genet 19: 1–25
Hamerton JL (1971) In: Human cytogenetics, Vol II. Academic Press, New York
Harvey PW, Mudal S, Wauchob D (1970) Antisocial behaviour and a large Y chromosome. Lancet 1:887
Hook EB (1973) Behavioral implications of the human XYY genotype. Science 179:139–150
Knuutila S, Grippenberg U (1972) The fluorescence pattern of a human Yq+ chromosome. Hereditas 70:307–308
Laberge C, Gagne R (1971) Quinacrine mustard staining solves the length variations of the human Y chromosome. Johns Hopkins Med J 128:79–83
Nielsen J, Friedrich U (1972) Length of the Y chromosome in criminal males. Clin Genet 3:281–285
Nielsen J, Nordland E (1975) Length of Y chromosome and activity in boys. Clin Genet 8:291–296
Pantil SR, Lubs HA (1977) A possible association of long Y chromosome and fetal loss. Hum Genet 35:233–235
Soudek D, Langmur V, Stewart DJ (1973) Variation in the non-fluorescent segment of long Y chromosome. Hum Genet 18:285–290
Soudek D, Laraya P (1974) Longer Y chromosome in criminals. Clin Genet 6:225–229
Verma RS, Dosik H, Scharf T, Lubs HA (1978) Length heteromorphisms of fluorescent (f) and non-fluorescent (nf) segments of human Y chromosome: classification, frequencies, and incidence in normal Caucasians. J Med Genet 15:277–281
Yamada K, Hasegawa T (1978) Types and frequencies of Q-variant chromosomes in a Japanese population. Hum Genet 44:89–98
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Yamada, K., Ohta, M., Yoshimura, K. et al. A possible association of Y chromosome heterochromatin with stature. Hum Genet 58, 268–270 (1981). https://doi.org/10.1007/BF00294920
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DOI: https://doi.org/10.1007/BF00294920