Summary
A panel of human-rodent somatic cell hybrids containing translocation derivatives of human chromosome 19 has been used to assign the markers peptidase D, complement component 3, lysosomal mannosidase, lysosomal DNAase, chorionic gonadotropin β-subunit, and a new polymorphic DNA sequence, to specific regions of chromosome 19. This has allowed the relative orientations of the genetic and physical maps to the established, and provides the framework for a search for the genes responsible for inherited disorders on chromosome 19, such as myotonic dystrophy and neurofibromatosis.
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Brook, J.D., Shaw, D.J., Meredith, L. et al. Localisation of genetic markers and orientation of the linkage group on chromosome 19. Hum Genet 68, 282–285 (1984). https://doi.org/10.1007/BF00292584
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DOI: https://doi.org/10.1007/BF00292584