Summary
Cells from an XX true hermaphrodite expressed a reduced amount of H-Y antigen when compared with normal XY cells and with cells from his father, who had an XY/XX chromosomal constitution. His mother had a normal karyotype and was H-Y negative. The four brothers of the patient were clinically and karyotypically normal. An X-Y interchange followed by random inactivation of the X chromosome is proposed to explain the H-Y antigen titer found in the patient.
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Moreira-Filho, C.A., Otto, P.G., Mustacchi, Z. et al. H-Y antigen expression in a case of XX true hermaphroditism. Hum Genet 55, 309–314 (1980). https://doi.org/10.1007/BF00290209
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DOI: https://doi.org/10.1007/BF00290209