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Regulation of the ilv 1 multifunctional gene in Saccharomyces cerevisiae

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Summary

  1. 1.

    The ilv1 gene in S. cerevisiae codes for a regulatory protein involved in depression of the ilv 2 and ilv 3 genes as well as a biosynthetic enzyme, threonine deaminase.

  2. 2.

    The ilv 1 gene does not autogenously regulate its catalytic product threonine deaninase.

  3. 3.

    Regulation of the ilv 2 and ilv 3 gene products involve different aporepressors than regulation of the ilv 1 gene product.

  4. 4.

    The ilv 1 multifunctional gene in S. cerevisiae may be a duplication and fusion of a bacterial like ilv 1 gene where ilv 1 catalytic and regulatory functions have been differentially conserved.

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Authors and Affiliations

  1. Biochemistry Department, The University of Texas, Southwestern Medical School, Dallas, Texas

    Arthur P. Bollon

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  1. Arthur P. Bollon
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Communicated by Gerard A. O'Donovan

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Bollon, A.P. Regulation of the ilv 1 multifunctional gene in Saccharomyces cerevisiae . Molec. Gen. Genet. 142, 1–12 (1975). https://doi.org/10.1007/BF00268750

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  • DOI: https://doi.org/10.1007/BF00268750

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