Summary
The proportion of magnified individuals in the progeny of bobbed males is dependant upon different factors: the bobbed allele used (Fig. 3), the age of the male (Table 2, 3) and the individual male tested (Table 1). From this, it can be thought that the first event leading to magnification happens before the separation of the germ line in the egg.
A number of individuals carrying bobbed alleles more extreme than the parental one were observed (Table 4); these alleles were lethal in combination with Ybb-. It cannot yet be acertained whether they are produced during the first step of magnification process itself or whether they originate later on.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Bibliographie
Gillespie, D., Spiegelman, S.: A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane. J. molec. Biol. 12, 829–842 (1965).
Henderson, A., Ritossa, F.: On the inheritance of rDNA of magnified bobbed loci in D. melanogaster. Genetics 66, 463–473 (1970).
Marrakechi, M., Prud'homme, N.: A study of bobbed mutants induced by ethyl methane sulfonate in Drosophila melanogaster. Biochem. biophys. Res. Commun. 43, 273–277 (1971).
Ritossa, F. M.: Unstable redundancy of genes for ribosomal RNA. Proc. nat. Acad. Sci. (Wash.) 60, 509–516 (1968).
Ritossa, F. M.: Nonoperative DNA complementary to ribosomal RNA. Proc. nat. Acad. Sci. (Wash.) 50, 1124–1131 (1968).
Ritossa, F. M., Atwood, K. C., Spiegelman, S.: A molecular explanation of bobbed mutants of Drosophila as partial deficiencies of “ribosomal” DNA. Genetics 54, 819–834 (1966).
Ritossa, F. M., Malva, C., Boncinelli, E., Graziani, F., Polito, L.: The first steps of magnification of DNA complementary to ribosomal RNA in Drosophila melanogaster. Proc. nat. Acad. Sci. (Wash.) 68, 1580–1584 (1971).
Ritossa, F. M., Scala, G.: Equilibrium variations in the redundancy of rDNA in Drosophila melanogaster. Genetics 61 (Suppl. n0 1 part. 2), 305–317 (1969).
Ritossa, F. M., Spiegelman, S.: Localization of DNA complementary to ribosomal RNA in the nucleolus organizer region of Drosophila melanogaster. Proc. nat. Acad. Sci. (Wash.) 53, 737–745 (1965).
Tartof, K. D.: Increasing the multiplicity of ribosomal RNA genes in Drosophila melanogaster. Science 71, 294–297 (1971).
Author information
Authors and Affiliations
Additional information
Mémoire présenté par G. Magni
Rights and permissions
About this article
Cite this article
Locker, D., Prud'homme, N. Etude de plusieurs facteurs faisant varier la fréquence de reversion au locus bobbed chez Drosophila melanogaster . Molec. Gen. Genet. 124, 11–19 (1973). https://doi.org/10.1007/BF00267160
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00267160