Summary
The influence of magnesium ions on the solubility and formation of calcium oxalate was studied. Both calcium oxalate mineral constituents of urinary calculi (whewellite and weddellite) were prepated in the presence of Mg2+-ions. For preparation, a gel growth technique and precipitation in aqueous solutions were used. The metastable weddellite formed only when Mg2+ concentration, reaction, temperature and precipitation velocity (see text) were combined in the proper way. It is concluded that Mg2+ions may induce an increase of solubility of calcium oxalate but in contrast also broaden the Ostwald-Miers range, thus favouring the formation of larger crystals.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Berg, W., Hesse, A., Schneider, H. J.: A contribution to the formation mechanism of calcium oxalate urinary calculi. III. On the role of Mg in the formation of oxalate calculi. Urological Research 4, 161 (1976)
Bisaillon, S., Tawashi, R.: Growth of calcium oxalate in gel systems. Journal of Pharmacentical Sciences 64, 458 (1975)
Desmars, J. F., Tawashi, R.: Dissolution and growth of calcium oxalate monohydrate. I. Effect of Mg and pH. Biochimica et Biophysica Acta 313, 256 (1973)
Elliot, J. S., Ribeiro, M. E.: Effect of varying concentrations of calcium and magnesium upon calcium oxalate solubility. Investigative Urology 10, 295 (1973)
Hammersten, G.: In: Gmelins Handbuch der anorganischen Chemie. Vol. Ca, Part B, Lieferung 3, p. 1006. Weinheim, Verlag Chemie 1961
Henisch, H. K.: Crystal growth in gels. University Park, London: Pennsylvania State University Press 1973
Le Geros, R. Z., Miravite, M. A., Quirolgico, G., Morales, P.: Factors influencing crystals growth and morphology of urinary stone crystallites. In: Colloquium on renal lithiasis. Finlayson, B., Thomas Jr. W. (eds.), Gainsville, University Press of Florida 1976
Le Geros, R. Z., Morales, P.: Renal stone crystals grown in gel systems. Investigative Urology 11, 12 (1973)
Meyer, J. L., Smith, L. H.: Growth of CaC2O4—crystals. II. Inhibition by natural urinary crystals growth inhibitors. Investigative Urology 13, 36 (1975)
Prien, E., Frondel, C.: Studies in urolithiasis. I. The composition of urinary calculi. Journal of Urology 57, 949 (1947)
Robertson, W. G., Peacock, M., Nordin, B. E. C.: Inhibitors of the growth and aggregation of calcium oxalate crystals in vitro. Clinica Chimica Acta 43, 31 (1973)
Treadwell, W. G.: Tabellen und Vorschriften zur Quantitativen Analyse. Wien: Franz Deutliche 1947
Wagner, S.: Kritischer Vergleich der Analysenmethoden der Harnwegskonkremente unter besonderer Berücksichtigung der kristalloptischen und röntgenographischen Verfahren. Berlin: Med. Diss. 1973
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wunderlich, W. Aspects of the influence of magnesium ions on the formation of calcium oxalate. Urol. Res. 9, 157–161 (1981). https://doi.org/10.1007/BF00264820
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00264820