Abstract
In a patient with viral pneumonia, acute respiratory and renal failure and metabolic acidosis, a reduction in left ventricular stroke work was observed on the three occasions that 100 ml of 8.4% sodium bicarbonate was infused. Blood pressure and cardiac output decreased on two of the occassions. Since intravenous sodium bicarbonate may produce adverse cardiovascular effects, a right heart catheter should be inserted to monitor these effects when alkali therapy is administered to an acutely ill patient with metabolic acidosis.
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Cooper, D.J., Worthley, L.I.G. Adverse haemodynamic effects of sodium bicarbonate in metabolic acidosis. Intensive Care Med 13, 425–427 (1987). https://doi.org/10.1007/BF00257690
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DOI: https://doi.org/10.1007/BF00257690