Summary
Axoplasmic transport of labelled proteins was studied in the vagus and hypoglossal nerves of the adolescent rabbit after an intramedullary injection of 3H-leucine.
As demonstrated by radioautography, the incorporated activity found in the intramedullary axons had a perikaryal origin and was transported distally at a rate of several mm per hour.
The migration of labelled proteins along the axons outside the medulla was followed by measuring the specific radioactivity of the proteins in the hypoglossal and vagus nerves. A rapid transport of labelled proteins in proximo-distal direction was demonstrated at rates of 16–17 mm/h in the vagus nerve and 10–15 mm/h in the hypoglossal nerve. The effect of puromycin and nerve ligature on the rapidly moving component is described.
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Sjöstrand, J. Rapid axoplasmic transport of labelled proteins in the vagus and hypoglossal nerves of the rabbit. Exp Brain Res 8, 105–112 (1969). https://doi.org/10.1007/BF00234533
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DOI: https://doi.org/10.1007/BF00234533