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De novo complex chromosomal rearrangement in a woman with recurrent spontaneous abortion and one healthy daughter

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Summary

Although rare, complex chromosomal rearrangements have been reported in the literature. The result is multiple congenital malformations in the offspring and recurrent spontaneous abortion. Chromosome 7 is usually involved, but in our patient chromosome 18 was involved.

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References

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Authors and Affiliations

  1. Department of Human Genetics and Teratology, National Institute of Hygiene — WHO Collaborating Centre for the Community Control of Hereditary Diseases, Gyáli út 2-6, H-1966, Budapest, Hungary

    László Timár, Judit Béres & Irén Németh

  2. Department of Pediatrics, Medical University of Pécs, Pécs, Hungary

    György Kosztolányi

Authors
  1. László Timár
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  2. Judit Béres
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  3. György Kosztolányi
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  4. Irén Németh
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Timár, L., Béres, J., Kosztolányi, G. et al. De novo complex chromosomal rearrangement in a woman with recurrent spontaneous abortion and one healthy daughter. Hum Genet 86, 421 (1991). https://doi.org/10.1007/BF00201851

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  • DOI: https://doi.org/10.1007/BF00201851

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