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Production of keratinolytic enzymes in a rotating frame bioreactor

  • Bioreactor Performance
  • Published:
Biotechnology Techniques

Summary

The keratin-degrading actinomycete Streptomyces fradiae was cultured in a bioreactor of novel design in which the wool substrate was wound over a supporting frame partially immersed in salts medium and slowly rotated during the course of fermentation. Both disulphide reductase and keratinase enzyme activities were detected in culture supernatants and the substrate was almost totally solubilized.

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Authors and Affiliations

  1. Department of Chemical Engineering, University of Technology, LE11 3TU, Loughborough, Leicestershire, UK

    Gilbert Shama

  2. Department of Chemical Engineering, University College Swansea, Singleton Park, SA2 9PP, Swansea, UK

    Paul G. Berwick

Authors
  1. Gilbert Shama
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  2. Paul G. Berwick
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Shama, G., Berwick, P.G. Production of keratinolytic enzymes in a rotating frame bioreactor. Biotechnol Tech 5, 359–362 (1991). https://doi.org/10.1007/BF00185014

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  • DOI: https://doi.org/10.1007/BF00185014

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