Summary
Cell cultures of the fruitfly, Drosophila melanogaster, were grown in a bioreactor to high cell densities: 5.7×107 cells/ml, in batch, semi-batch and continuous flow modes. Using a semi-batch culture mode 500g wet weight of cell mass was produced in 16 days, using 5 l of cheap, commercially available, serum-free medium.
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Søndergaard, L. Drosophila cells can be grown to high cell densities in a bioreactor. Biotechnol Tech 10, 161–166 (1996). https://doi.org/10.1007/BF00158939
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DOI: https://doi.org/10.1007/BF00158939