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Cisplatin-induced gastric paresis

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Summary

A 27 year old male with metastatic testicular carcinoma was treated with cisplatin, vinblastine, and bleomycin (PVB) chemotherapy. After receiving a cumulative dose of 500 mg/m2 of cisplatin, he developed severe nausea and vomiting and had clinical evidence of a cisplatin-induced peripheral neuropathy. His vomiting resolved five weeks after discontinuation of cisplatin. We believe this case represents the first report of gastric autonomic neuropathy induced by cisplatin.

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Authors and Affiliations

  1. Department of Medicine (Hematology-Oncology), Hospital of the University of Pennsylvania, 3400 Spruce Street, 19104, Philadelphia, PA, USA

    Steven C. Cohen

  2. Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 19104, Philadelphia, PA, USA

    Joan E. Mollman

Authors
  1. Steven C. Cohen
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  2. Joan E. Mollman
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Cohen, S.C., Mollman, J.E. Cisplatin-induced gastric paresis. J Neuro-Oncol 5, 237–240 (1987). https://doi.org/10.1007/BF00151227

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  • DOI: https://doi.org/10.1007/BF00151227

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